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Table 1 Intestine transcripts corresponding to the top 100 most significant features exhibiting differential expression between diets

From: Effects of genotype and dietary fish oil replacement with vegetable oil on the intestinal transcriptome and proteome of Atlantic salmon (Salmo salar)

Accession no Gene VO/FO p- value
   Lean Fat  
Metabolism (39%)
Lipid metabolism (9%)
DW590668 Fatty aldehyde dehydrogenase - 1.1 - 1.2 0.0003
CK888998 Ethanolamine kinase 1 1.2 1.2 0.0008
CK884623 Epidermis-type arachidonate lipoxygenase 3 1.4 1.1 0.0010
CK885725 Protein containing a beta-ketoacyl synthase domain 1.4 1.6 0.0017
AF478472 Delta-5 fatty acyl desaturase 1.2 2.5 0.0019
Energy metabolism/generation of precursor metabolites (11%)
CK885194 Cytochrome c oxidase subunit 5A - 1.2 - 1.1 0.0000
bra_snb_03E12 NADH dehydrogenase subunit 1 - 1.3 - 1.2 0.0000
EG649067 Ubiquinol-cytochrome c reductase core protein 1 - 1.2 - 1.1 0.0004
CK884638 Uncoupling protein - 1.3 −1.3 0.0019
CK890974 Mitochondrial calcium-dependent solute carrier SCaMC-2 - 1.5 1.0 0.0021
EG648806 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 9 - 1.1 - 1.1 0.0022
Protein and amino acid metabolism (9%)
CK877521 Kunitz-type protease inhibitor 2 precursor 1.2 1.1 0.0002
DW590246 Betaine aldehyde dehydrogenase - 1.4 - 1.0 0.0005
CK885180 Fumarylacetoacetate hydrolase domain-containing protein 2B - 1.4 - 1.3 0.0007
CK897653 Ubiquitin-conjugating enzyme E2 A 1.2 1.2 0.0012
CK885145 Lysosomal protective protein precursor (Cathepsin A) 1.1 1.1 0.0014
Carbohydrate metabolism (5%)
EG649263 Endosulfine alpha - 1.3 - 1.0 0.0005
CK885545 Glucose transporter type 8 1.0 1.5 0.0013
Xenobiotic and oxidant metabolism (5%)
CK885392 Catalase 1.6 1.1 0.0000
CO472279 Cytochrome P450 1a 1.2 1.4 0.0004
CK898307 Selenoprotein H-like protein 1.3 1.1 0.0013
Transport/ intracellular trafficking (5%)
EG647578 Calcium-activated potassium channel subunit alpha 1 1.3 1.2 0.0005
EG648841 Sodium-coupled neutral amino acid transporter 2 - 1.2 - 1.2 0.0007
EG648303 Mitochondrial import receptor subunit TOM20 homolog - 1.1 - 1.1 0.0011
Regulation of transcription (13%)
CK898304 C-Maf 1.6 1.6 0.0000
CK890154 Butyrate response factor 2 1.6 1.2 0.0001
EG647831 Proliferation-associated 2G4 b - 1.3 - 1.2 0.0003
AM041851 Enhancer trap locus homolog 1 - 1.1 - 1.2 0.0004
CK885179 Steroid receptor RNA activator 1 - 1.3 - 1.3 0.0007
CK884728 Butyrate response factor 1 1.1 1.4 0.0011
CK879187 Enhancer of polycomb homolog 1 1.4 1.1 0.0020
Translation (17%)
CK878380 40S ribosomal protein S18 - 1.1 - 1.2 0.0003
DW591873 60S acidic ribosomal protein - 1.3 - 1.2 0.0006
EG648644 60S ribosomal protein L29 - 1.1 - 1.2 0.0011
DW590580 40S ribosomal protein S5 - 1.2 - 1.2 0.0011
CK880046 40S ribosomal protein S28 - 1.1 - 1.2 0.0017
EG649167 60S ribosomal protein L37a - 1.1 - 1.2 0.0017
EG648512 60S ribosomal protein L41 - 1.1 - 1.2 0.0017
CK886042 60S ribosomal protein L31 - 1.1 - 1.3 0.0021
CK895350 60S ribosomal protein L36 - 1.1 - 1.1 0.0021
Signalling/Signal transduction (17%)
CK874863 Proto-oncogene serine/threonine-protein kinase 1.1 1.1 0.0002
CK881266 Mitogen-activated protein kinase kinase kinase kinase 1 1.2 1.2 0.0002
CK878590 Serine/threonine protein kinase (Tribbles homolog 2) - 1.1 - 1.3 0.0004
AJ425351 Tensin-like C1 domain-containing - 2.0 - 1.2 0.0006
CK885079 Sonic hedgehog-like protein 1.3 1.0 0.0008
CN181161 TGF-beta type II receptor 1.1 1.1 0.0009
EG649257 Serine/threonine-protein kinase VRK3 - 1.1 - 1.2 0.0009
CK886267 Guanylate cyclase 2C 1.1 1.1 0.0011
CK884467 Serine/threonine-protein phosphatase 2A regulatory subunit B - 1.4 - 1.3 0.0020
Structural proteins (7%)
mus_snm_13F09 Myosin heavy chain - 1.2 - 1.1 0.0002
CK885118 Cardiac tropomyosin 1.0 1.1 0.0013
CK883354 Troponin C 1.2 1.2 0.0017
EG647866 Tubulin alpha chain - 1.2 - 1.2 0.0020
Immune response (2%)
BM414177 Liver-expressed antimicrobial peptide 2 1.5 1.4 0.0022
Miscellaneous
CK884634 Ezrin-radixin-moesin binding phosphoprotein 50 1.1 1.1 0.0003
EG648821 Transposase - 1.1 - 1.2 0.0004
CK883634 Poly [ADP-ribose] polymerase 12 1.3 1.1 0.0006
CK885090 Claudin 15 1.2 1.1 0.0008
DW589291 Transposase - 1.3 - 1.3 0.0009
CK878888 Splicing factor, arginine/serine-rich 3 - 1.3 - 1.2 0.0013
CK885098 RNA-binding protein with multiple splicing 2 - 1.4 - 1.2 0.0013
CK891747 Occludin - 1.2 - 1.2 0.0014
CK888908 All-trans-retinol 13,14-reductase precursor 1.1 1.2 0.0017
CK880622 Cyclin G1 - 1.1 - 1.2 0.0019
CK885604 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like - 1.6 - 1.3 0.0020
CK891699 Barrier-to-autointegration factor - 1.1 - 1.2 0.0020
CK879123 Hemoglobin subunit beta 1.5 1.0 0.0022
  1. Annotated features (67% of all clones) are arranged by categories of biological function (with percentages of distribution of genes within each category being indicated) and, within these, by decreasing significance (assessed by two-way ANOVA). Also indicated are the GenBank accession numbers for each clone (or, when not available, the probe number) and the expression ratio between fish fed VO and those fed FO, for each genotype (Lean and Fat).