Comparative genomics of Brachyspira pilosicoli strains: genome rearrangements, reductions and correlation of genetic compliment with phenotypic diversity

Table 1 General genome feature comparison for B. pilosicoli strains of different host origin

Genome features	95/1000	B2904	WesB^a
Genome size (bp)	2586443	2765477	2889522
G+C content	27.90%	27.79%	27.45%
Total predicted ORFs	2339	2696	2690
Non-significant PID and coverage ORFs	3	23	101
Significant PID and/or coverage ORFs	2336	2673	2589
rRNA genes	3	3	3
tRNA genes	34	34	34
tmRNA genes	1	1	1
hypothetical/conserved hypothetical proteins	657	590	545
genes with function prediction	1641	2045	2006
Genes assigned to COG^b	1201	1196	1276
Genes assigned a KO number^bc	1048	1082	1128
Genes assigned E.C. numbers^b	523	567	563
Genes with signal peptide	244	322	316
Genes with transmembrane helices	48	61	68
Mobile genetic elements (MGE)	4	61	31
insertion sequence elements (ISE)	0	15	17
integrases	0	43	10
transposases	2	1	2
recombinases	2	2	2
Suspected truncated proteins	55	130	64
Suspected protein frameshift/deletions	4	223	50

The comparison includes strains 95/1000 (porcine), B2904 (avian) and WesB (human).
^a The incomplete WesB strain genome was within one scaffold.
^b Those genes with significant PID and/or query/target coverage hits; significance equals blastx/blastp PID of at least 25% and/or 75% query or target coverage.
^c Assigned to KO via KEGG Automatic Annotation Server (KAAS)

ISSN: 1471-2164