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Table 4 GO term enrichment analysis for artifactual and putative AED events

From: Controversies in modern evolutionary biology: the imperative for error detection and quality control

GO enrichment for all events

GO enrichment for true events only

GO ID

GO biological process

P-value

GO ID

GO biological process

P-value

0032501

multicellular organismal process

4.E-43

0032501

multicellular organismal process

2.E-13

0048856

anatomical structure development

2.E-32

0050896

response to stimulus

9.E-12

0065007

biological regulation

4.E-26

0048856

anatomical structure development

3.E-09

0080090

regulation of primary metabolic process

6.E-21

0042060

wound healing

2.E-07

0071842

cellular component organization at cellular level

3.E-20

0050789

regulation of biological process

1.E-06

0060255

regulation of macromolecule metabolic process

5.E-19

0071842

cellular component organization at cellular level

2.E-06

0051171

regulation of nitrogen compound metabolic process

5.E-19

0007596

blood coagulation

4.E-06

0032774

RNA biosynthetic process

5.E-16

0022008

neurogenesis

5.E-05

2000112

regulation of cellular macromolecule biosynthetic process

7.E-16

0006928

cellular component movement

6.E-05

0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

1.E-15

0030182

neuron differentiation

4.E-04

0010467

gene expression

4.E-13

   

0042060

wound healing

4.E-09

   

0007596

blood coagulation

2.E-08

   

0006810

transport

2.E-08

   

0007166

cell surface receptor linked signaling pathway

3.E-06

   

0007411

axon guidance

5.E-06

   

0007601

visual perception

2.E-05

   

0016477

cell migration

5.E-05

   

0030168

platelet activation

1.E-04

   

0006195

purine nucleotide catabolic process

1.E-04

   

0009207

purine ribonucleoside triphosphate catabolic process

5.E-04

   

0016568

chromatin modification

6.E-04

   

0006915

apoptosis

8.E-04

   

0060173

limb development

9.E-04

   
  1. Comparison of GO term enrichment analysis for (i) gene list 1 corresponding to 607 predicted asymmetrical evolution events, including both artifactual and putative true events and (ii) 25O true events obtained after filtering the erroneous sequences. GO terms for biological processes were found with P < 10-4 using AmiGO and then filtered with GO-Module (only key terms are shown). Terms that are specific to only one gene list are highlighted in bold.
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BMC Genomics

ISSN: 1471-2164

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