Figure 2From: Development of the first oligonucleotide microarray for global gene expression profiling in guinea pigs: defining the transcription signature of infectious diseasesPulmonary pathology in M. tuberculosis infected guinea pigs. The figure depicts (A) representative photograph showing gross pathology of lungs of M. tuberculosis infected guinea pigs at 10 weeks post-infection; (B) lower magnification photomicrograph of H&E stained, formalin fixed and paraffin embedded 5 μm section of lung tissue exhibiting multiple coalescing granulomas with central necrotic core and (C) photomicrograph (at 40X) of Van Gieson stained 5 μm lung section exhibiting extensive fibrosis as evident from thick bands of collagen (red color) around the granulomatous regions. Scale bar represents 1000 μm.Back to article page