Figure 5

Network 1 as generated by IPA. The significant biological functions comprising this network are lipid metabolism, small molecule biochemistry and vitamin and mineral metabolism. The network is displayed graphically as nodes (gene/gene products) and edges (the biological relationship between nodes). The node colour indicates the expression of genes: (red) up-regulated and (green) down-regulated in H group relative to L group. The shapes of nodes indicate the functional classes of the gene products. Relevant canonical pathways that feature modulated genes were indicted as well (e.g. Arachidonic Acid metabolism, PPARα/RXRα and PXR/RXR Activation).