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Table 2 The top ten molecular functions associated with HBc-immunoprecipitated host promoter sequences

From: Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions

Molecular function

Count*

p-value**

FDR***

Binding

2022

6.4000E-11

2.5632E-08

Protein binding

1398

9.7000E-13

7.7697E-10

Catalytic activity

881

2.8000E-06

2.8035E-04

Ion binding

702

9.4800E-03

1.3559E-01

Cation binding

697

4.9800E-03

8.3437E-02

Metal ion binding

692

4.2500E-03

8.3030E-02

Nucleotide binding

392

4.9000E-04

2.0657E-02

Purine nucleotide binding

339

6.2000E-04

02.4831E-02

Transferase activity

337

2.0000E-08

5.3400E-06

Ribonucleotide binding

328

3.6000E-04

1.7434 E-02

Transcription regulator activity

289

2.4000E-06

2.7463E-04

  1. * Number of genes associated with the corresponding molecular function
  2. ** Significance testing value of genes associated with the corresponding molecular function.
  3. *** False discovery rate of genes associated with the corresponding molecular function, as determined by the Benjamini & Hochberg (1995) testing method.