MDL of exon microarray and tag-seq. MDL plotted as a function of sample purity by (A) exon microarray and (B) tag-seq. Full drawn black line is the MDL estimate from the experiment. Dotted lines show MDL for a range of standard errors (exon) and dispersion parameters (tag-seq). IDL is the instrument detection limit defined as 367 when 95% confidence was used for exon microarrays and 18 for tag-seq when the linear mean-variance negative binomial regression was used. In the pure sample detection of signal is not possible below the IDL.