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Table 1 Summary statistics for genes predicted to show an age-related, astrocyte-specific change in expression

From: Cell population-specific expression analysis of human cerebellum

Probe ID Expr (A) p (A) DE (dA) p (dA) ME adj. R2 Gene symb. Gene title, transcript variant
ILMN_1653001 323 6.0 × 10-9 245 2.5 × 10-6 849 0.69 CABLES1 Cdk5 and Abl enzyme substrate 1
ILMN_1751904 802 6.1 × 10-16 −283 1.1 × 10-5 1009 0.86 EDNRB endothelin receptor type B (EDNRB), transcript variant 2
ILMN_1813597 1792 7.6 × 10-21 −410 4.7 × 10-5 2333 0.93 C4orf18 chromosome 4 open reading frame 18 (C4orf18), transcript variant 1
ILMN_1796755 229 1.5 × 10-9 −119 7.4 × 10-5 604 0.76 ITGB5 integrin, beta 5 (ITGB5)
ILMN_1801377 863 6.2 × 10-08 −491 1.4 × 10-4 2077 0.80 SLC29A4 solute carrier family 29 (nucleoside transporters), member 4 (SLC29A4)
ILMN_1757180 67 5.8 × 10-07 41 2.1 × 10-4 303 0.76 WDR49 WD repeat domain 49 (WDR49)
ILMN_1732197 276 1.7 × 10-12 −98 2.3 × 10-4 586 0.86 MN1 meningioma (disrupted in balanced translocation) 1 (MN1)
ILMN_1685641 118 4.0 × 10-6 −75 5.4 × 10-4 438 0.79 BCHE butyrylcholinesterase (BCHE)
ILMN_1754795 1459 4.5 × 10-7 −771 9.3 × 10-4 3588 0.76 FAT FAT tumor suppressor homolog 1 (Drosophila) (FAT)
ILMN_1688868 1296 5.6 × 10-16 −314 1.1 × 10-3 1676 0.90 PPAP2B phosphatidic acid phosphatase type 2B (PPAP2B), transcript variant 1
ILMN_1717636 1735 1.5 × 10-15 −492 1.1 × 10-3 2610 0.79 RGMA RGM domain family, member A (RGMA)
ILMN_1800317 144 1.4 × 10-11 −48 1.3 × 10-3 364 0.84 WNT5A wingless-type MMTV integration site family, member 5A (WNT5A)
ILMN_1738147 449 3.1 × 10-6 −260 1.5 × 10-3 996 0.56 NES nestin (NES)
ILMN_1815102 1065 1.0 × 10-9 −416 1.5 × 10-3 1764 0.78 LCAT lecithin-cholesterol acyltransferase (LCAT)
ILMN_1709486 1717 9.5 × 10-19 −321 2.3 × 10-3 2253 0.91 SRPX sushi-repeat-containing protein, X-linked (SRPX)
  1. The top 15 genes with the most significant expression changes are listed. Expr (A): astrocyte-specific expression level, p: p-value, DE (dA): astrocyte-specific differential expression, ME: mean expression, adj. R2: adjusted R2.