Table 1 Summary statistics for genes predicted to show an age-related, astrocyte-specific change in expression
From: Cell population-specific expression analysis of human cerebellum
Probe ID | Expr (A) | p (A) | DE (dA) | p (dA) | ME | adj. R2 | Gene symb. | Gene title, transcript variant |
|---|---|---|---|---|---|---|---|---|
ILMN_1653001 | 323 | 6.0 × 10-9 | 245 | 2.5 × 10-6 | 849 | 0.69 | CABLES1 | Cdk5 and Abl enzyme substrate 1 |
ILMN_1751904 | 802 | 6.1 × 10-16 | −283 | 1.1 × 10-5 | 1009 | 0.86 | EDNRB | endothelin receptor type B (EDNRB), transcript variant 2 |
ILMN_1813597 | 1792 | 7.6 × 10-21 | −410 | 4.7 × 10-5 | 2333 | 0.93 | C4orf18 | chromosome 4 open reading frame 18 (C4orf18), transcript variant 1 |
ILMN_1796755 | 229 | 1.5 × 10-9 | −119 | 7.4 × 10-5 | 604 | 0.76 | ITGB5 | integrin, beta 5 (ITGB5) |
ILMN_1801377 | 863 | 6.2 × 10-08 | −491 | 1.4 × 10-4 | 2077 | 0.80 | SLC29A4 | solute carrier family 29 (nucleoside transporters), member 4 (SLC29A4) |
ILMN_1757180 | 67 | 5.8 × 10-07 | 41 | 2.1 × 10-4 | 303 | 0.76 | WDR49 | WD repeat domain 49 (WDR49) |
ILMN_1732197 | 276 | 1.7 × 10-12 | −98 | 2.3 × 10-4 | 586 | 0.86 | MN1 | meningioma (disrupted in balanced translocation) 1 (MN1) |
ILMN_1685641 | 118 | 4.0 × 10-6 | −75 | 5.4 × 10-4 | 438 | 0.79 | BCHE | butyrylcholinesterase (BCHE) |
ILMN_1754795 | 1459 | 4.5 × 10-7 | −771 | 9.3 × 10-4 | 3588 | 0.76 | FAT | FAT tumor suppressor homolog 1 (Drosophila) (FAT) |
ILMN_1688868 | 1296 | 5.6 × 10-16 | −314 | 1.1 × 10-3 | 1676 | 0.90 | PPAP2B | phosphatidic acid phosphatase type 2B (PPAP2B), transcript variant 1 |
ILMN_1717636 | 1735 | 1.5 × 10-15 | −492 | 1.1 × 10-3 | 2610 | 0.79 | RGMA | RGM domain family, member A (RGMA) |
ILMN_1800317 | 144 | 1.4 × 10-11 | −48 | 1.3 × 10-3 | 364 | 0.84 | WNT5A | wingless-type MMTV integration site family, member 5A (WNT5A) |
ILMN_1738147 | 449 | 3.1 × 10-6 | −260 | 1.5 × 10-3 | 996 | 0.56 | NES | nestin (NES) |
ILMN_1815102 | 1065 | 1.0 × 10-9 | −416 | 1.5 × 10-3 | 1764 | 0.78 | LCAT | lecithin-cholesterol acyltransferase (LCAT) |
ILMN_1709486 | 1717 | 9.5 × 10-19 | −321 | 2.3 × 10-3 | 2253 | 0.91 | SRPX | sushi-repeat-containing protein, X-linked (SRPX) |