Glucocorticoid receptor target genes are differentially expressed in response to CA04 virus. Average log10(ratio) expression of downstream GR target genes induced by CA04 virus. In mice and swine, infected lung gene expression is referenced to specie-matched mock at each time point. In macaques, infected lung gene expression is relative to an uninfected lung reference pool at each time point. Red indicates expression was increased relative to the control reference and green indicates that expression was decreased relative to the control reference. Saturation is 4-fold.