From: An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control
Kinetochore | |
---|---|
Bub1 | Spindle assembly protein. |
Cbf2 | Essential kinetochore protein, component of the CBF3 multisubunit complex. |
Cnn1 | Kinetochore protein of unknown function. |
Mad1 | Spindle assembly protein. |
Spc105 | Subunit of a kinetochore-microtubule binding complex that bridges centromeric heterochromatin and kinetochore. Required for kinetochore binding of SAC proteins. |
Tid3 | Component of the evolutionarily conserved kinetochore-associated Ndc80 complex. |
Mitotic spindle | |
Bub2 | Mitotic exit network regulator. |
Nud1 | Component of the spindle pole body outer plaque, required for exit from mitosis. |
Spc72 | Binds spindle pole bodies and links them to microtubules. |
Spc97 | Interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque. |
Spc110 | Inner plaque spindle pole body (SPB) component. |
Stu1 | Component of the mitotic spindle that binds to interpolar microtubules. |
Cytokinesis | |
Cdc3 | Component of the septin ring of the mother-bud neck that is required for cytokinesis. |
Cla4 | Involved in septin ring assembly and cytokinesis. |
Cts1 | Required for cell separation after mitosis. |
Dse4 | Degrades cell wall from the daughter side causing daughter to separate from mother. |
Egt2 | Required for proper cell separation after cytokinesis. |
Elm1 | Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis. |
Cell bud | |
Ace2 | Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters. |
Bud3 | Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis. |
Bud8 | Protein involved in bud-site selection. |
Num1 | Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip. |
She3 | Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud. |
Cortical Actin cytoskeleton | |
Akl1 | Ser-Thr protein kinase involved in endocytosis and actin cytoskeleton organization. |
Ark1 | Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton. |
Bni1 | Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation. |
Las17 | Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments. |
Ndl1 | Regulates dynein targeting to microtubule plus ends. |
Sda1 | Required for actin cytoskeleton organization. |