Figure 6
From: Weighted pedigree-based statistics for testing the association of rare variants
The power curves of the family-based collapsing test (variants with frequencies ≤0.005 were collapsed) statistic as a function of the proportion of risk variants at the significance level α = 0.05 in the test under seven settings: unrelated individuals in cases-controls study, nuclear family groups 1 and 2, sib-pair groups 1 and 2 and three generation family groups 1 and 2, assuming a dominant model, a total of 1,800 sampled individuals and a baseline penetrance of 0.01.