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Figure 1 | BMC Genomics

Figure 1

From: A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease

Figure 1

Expression of REST signature genes in glioma tumors and non-neoplastic brain tissue. Expression REST signature genes (y-axis) are compared between 176 glioma tumors and non-neoplastic brain tissues (x-axis) from NCBI dataset GSE4290. Non-neoplastic brain tissue shows significantly greater REST target gene expression than many of the oligodendroma and astrocytomas. Average expression of normalized REST target genes is displayed below as mean +/- standard error. Oligodendromas and astrocytomas both show decreased REST target gene expression with increasing tumor grade. All heatmaps and tumor analyses were performed using MultiExperiment Viewer v4.6.

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