Expression of REST signature genes in glioma tumors and non-neoplastic brain tissue. Expression REST signature genes (y-axis) are compared between 176 glioma tumors and non-neoplastic brain tissues (x-axis) from NCBI dataset GSE4290. Non-neoplastic brain tissue shows significantly greater REST target gene expression than many of the oligodendroma and astrocytomas. Average expression of normalized REST target genes is displayed below as mean +/- standard error. Oligodendromas and astrocytomas both show decreased REST target gene expression with increasing tumor grade. All heatmaps and tumor analyses were performed using MultiExperiment Viewer v4.6.