Figure 6From: A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive diseaseCorrelation of BTRC mRNA and REST signature gene levels. (A) Mean normalized REST signature gene and BTRC mRNA levels are plotted for 2 non-neoplastic and 200 GBM tissue samples from the cancer genome atlas’ (TCGA) unified and scaled gene expression dataset [21]. A strong correlation between REST function and BTRC mRNA levels is confirmed to be statistically significant using the Kendall’s rank correlation test p-value (p<10-17). (B) Scatter plot of data in (A). Statistical analyses were performed using the Mstat software package (http://www.mcardle.wisc.edu/mstat/).Back to article page