Gene symbol | Correlation | RE1 Site | ChiP | Summary |
---|---|---|---|---|
NF1 | p<0.000005 | Intronic-TCTAGAACCAAGGCCAG | Abrajano | RasGAP tumorsuppressor. Loss of NF1 by mutation or degradation occurs in many gliomas and is associated with chemotherapy resistance |
BEX1 | p<10^-16 | Intronic-TCTAGAACCAAGGCCAG | Johnson | Suppresses growth of glioma xenografts, reintroduction of BEX1 in glioma cell lines induces chemotherapy sensitivity |
CDKN1B/p27KIP1 | p<10^-9 | Upstream-TCTAGAACCAAGGCCAG | - | Glioma tumor suppressor known to regulate cell growth, apaptosis and sensitivity to chemotherapy |
mIR-124 | p<10^-29 | Multiple | Conaco | Glioma tumor suppressor that regulates proliferation and differentiation |