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Table 1 Conservation of active site residues of C. glutamicum (2S,3S)-2,3-butanediol dehydrogenase in Pcar _0903, Pcar _2068 and Ppro _3110, compared to meso-2,3-butanediol dehydrogenase of K. pneumoniae

From: The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features

C. glutamicum

K. pneumoniae

Pcar_0903 BudY

Pcar_2068 BudZ

Ppro_3110

S141

S139

S151

C144

S148

I142

Q140

I152

I145

I149

A143

A141

A153

A146

A150

F148

N146

F158

L151

F155

Y154

Y152

Y164

Y157

Y161

P184

P182

P194

P187

P191

G185

G183

G195

G188

G192

I186

I184

I196

I189

I193

M191

M189

M201

M194

M198

W192

W190

W202

W195

W199

I195

I193

I205

I198

I202

  1. Mutations that could alter the substrate specificity from (2S,3S)-2,3-butanediol to meso-2,3-butanediol are indicated in italics.
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BMC Genomics

ISSN: 1471-2164

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