Table 2 Mechanistic responses in Atlantic cod larvae exposed to chemically (CD) or mechanically (MD) dispersed oil droplets for four days
Group | Name | p-value | Ratio | Group | Name | p-value | Ratio |
|---|---|---|---|---|---|---|---|
CDH | Positive Acute Phase Response Proteins | 5.1E-05 | 6/30 (0.2) | MDH | Negative Acute Phase Response Proteins | 2.07E-05 | 5/8 (0.625) |
CDH | Aryl Hydrocarbon Receptor Signaling | 2.66E-04 | 12/157 (0.076) | MDH | p53 Signaling | 4.86E-04 | 14/95 (0.147) |
CDH | Cell Cycle: G1/S Checkpoint Regulation | 3.04E-04 | 7/57 (0.123) | MDH | Liver Proliferation | 7.01E-04 | 17/133 (0.128) |
CDH | Negative Acute Phase Response Proteins | 6.08E-04 | 3/8 (0.375) | MDH | Oxidative Stress | 7.68E-04 | 10/57 (0.175) |
CDH | Fatty Acid Metabolism | 2.06E-03 | 9/123 (0.073) | MDH | Cholesterol Biosynthesis | 1.13E-03 | 5/16 (0.312) |
CDM | FXR/RXR Activation | 3.6E-07 | 6/87 (0.069) | MDM | Aryl Hydrocarbon Receptor Signaling 4 | 6.02E-04 | 5/157 (0.032) |
CDM | LXR/RXR Activation | 2.28E-06 | 6/119 (0.05) | MDM | Xenobiotic Metabolism Signaling | 7.95E-04 | 7/349 (0.02) |
CDM | Positive Acute Phase Response Proteins | 2.52E-06 | 4/30 (0.133) | MDM | Cytochrome P450 Panel - Substrate is a Xenobiotic (Human) | 2.71E-03 | 2/18 (0.111) |
CDM | Fatty Acid Metabolism | 6.67E-04 | 4/123 (0.033) | MDM | NRF2-mediated Oxidative Stress Response | 3.69E-03 | 5/237 (0.021) |
CDM | Xenobiotic Metabolism Signaling | 8.92E-04 | 6/349 (0.017) | ||||
MDL | Negative Acute Phase Response Proteins | 3.6E-05 | 2/8 (0.25) | ||||
MDL | Decreases Respiration of Mitochondria | 7.05E-05 | 2/11 (0.182) | ||||
MDL | LXR/RXR Activation | 3.42E-04 | 3/119 (0.025) | ||||
MDL | TR/RXR Activation | 4.45E-03 | 2/86 (0.023) |