Table 5 Enriched transcription factor binding sites in the promoters of genes, obtained from H9c2 cells treated with CBHA or TSA*
CBHA 6h | ||||
|---|---|---|---|---|
Transcription factors | # exp promoters hit | # exp promoters | P value | Q value |
AP2_Q6 | 584 | 658 | 0 | 0 |
CHCH_01 | 617 | 658 | 0 | 0 |
E2F_Q2 | 548 | 658 | 0 | 0 |
E2F1_Q3_01 | 317 | 658 | 0 | 0 |
EGR2_01 | 592 | 658 | 0 | 0 |
ETF_Q6 | 412 | 658 | 0 | 0 |
GC_01 | 584 | 658 | 0 | 0 |
KROX_Q6 | 411 | 658 | 0 | 0 |
LRF_Q2 | 456 | 658 | 0 | 0 |
MAZR_01 | 233 | 658 | 0 | 0 |
NGFIC_01 | 434 | 658 | 0 | 0 |
SP1_Q6_01 | 558 | 658 | 0 | 0 |
WT1_Q6 | 528 | 658 | 0 | 0 |
AHRHIF_Q6 | 361 | 658 | 1.00E-09 | 2.25E-08 |
MUSCLE_INI_B | 593 | 658 | 1.93E-08 | 3.97E-07 |
AHRARNT_02 | 336 | 658 | 1.54E-07 | 3.03E-06 |
SPZ1_01 | 605 | 658 | 1.77E-07 | 3.35E-06 |
AP2ALPHA_01 | 596 | 658 | 3.81E-07 | 6.21E-06 |
AP2GAMMA_01 | 622 | 658 | 3.63E-07 | 6.21E-06 |
MAZ_Q6 | 315 | 658 | 3.70E-07 | 6.21E-06 |
UF1H3BETA_Q6 | 31 | 658 | 1.20E-05 | 1.89E-04 |
CACBINDINGPROTEIN_Q6 | 431 | 658 | 1.26E-05 | 1.92E-04 |
MOVOB_01 | 647 | 658 | 3.16E-05 | 4.44E-04 |
VDR_Q3 | 603 | 658 | 3.42E-05 | 4.62E-04 |
ZF5_B | 655 | 658 | 9.53E-05 | 1.25E-03 |
E2F1DP2_01 | 293 | 658 | 1.48E-04 | 1.89E-03 |
NFY_Q6_01 | 226 | 658 | 2.11E-04 | 2.62E-03 |
CACD_01 | 635 | 658 | 2.61E-04 | 3.16E-03 |
MZF1_02 | 571 | 658 | 3.58E-04 | 4.23E-03 |
CACCCBINDINGFACTOR_Q6 | 78 | 658 | 4.56E-04 | 5.26E-03 |
WHN_B | 145 | 658 | 4.92E-04 | 5.54E-03 |
CBHA 24h | ||||
AP2_Q6 | 728 | 847 | 0 | 0 |
AP2ALPHA_01 | 776 | 847 | 0 | 0 |
CHCH_01 | 794 | 847 | 0 | 0 |
E2F_Q2 | 680 | 847 | 0 | 0 |
E2F1_Q3_01 | 379 | 847 | 0 | 0 |
EGR_Q6 | 604 | 847 | 0 | 0 |
ETF_Q6 | 492 | 847 | 0 | 0 |
GC_01 | 737 | 847 | 0 | 0 |
KROX_Q6 | 486 | 847 | 0 | 0 |
MAZR_01 | 256 | 847 | 0 | 0 |
NGFIC_01 | 532 | 847 | 0 | 0 |
SP1_01 | 697 | 847 | 0 | 0 |
WT1_Q6 | 682 | 847 | 0 | 0 |
LRF_Q2 | 559 | 847 | 2.00E-10 | 4.68E-09 |
MZF1_02 | 759 | 847 | 2.00E-10 | 4.68E-09 |
SPZ1_01 | 780 | 847 | 1.80E-09 | 4.02E-08 |
AP2GAMMA_01 | 802 | 847 | 3.60E-09 | 7.33E-08 |
MOVOB_01 | 837 | 847 | 1.79E-08 | 3.49E-07 |
CACBINDINGPROTEIN_Q6 | 555 | 847 | 8.55E-07 | 1.48E-05 |
CACD_01 | 822 | 847 | 1.19E-06 | 1.99E-05 |
CACCCBINDINGFACTOR_Q6 | 108 | 847 | 2.31E-06 | 3.72E-05 |
AHRHIF_Q6 | 431 | 847 | 3.66E-06 | 5.53E-05 |
NFY_Q6_01 | 294 | 847 | 1.24E-05 | 1.77E-04 |
E2F1DP2_01 | 378 | 847 | 1.64E-05 | 2.26E-04 |
AHRARNT_02 | 408 | 847 | 1.99E-05 | 2.67E-04 |
MAZ_Q6 | 382 | 847 | 3.46E-05 | 4.51E-04 |
STRA13_01 | 32 | 847 | 8.99E-05 | 1.08E-03 |
SP3_Q3 | 821 | 847 | 3.89E-04 | 4.14E-03 |
VDR_Q3 | 766 | 847 | 4.08E-04 | 4.24E-03 |
MUSCLE_INI_B | 733 | 847 | 7.95E-04 | 8.10E-03 |
TSA 6h | ||||
E2F_Q2 | 319 | 390 | 0 | 0 |
E2F1_Q3_01 | 187 | 390 | 0 | 0 |
ETF_Q6 | 243 | 390 | 0 | 0 |
GC_01 | 341 | 390 | 0 | 0 |
KROX_Q6 | 233 | 390 | 0 | 0 |
SP1_Q6_01 | 320 | 390 | 0 | 0 |
CHCH_01 | 361 | 390 | 8.00E-10 | 3.33E-08 |
MAZR_01 | 128 | 390 | 1.70E-09 | 6.52E-08 |
EGR2_01 | 350 | 390 | 1.66E-08 | 5.52E-07 |
WT1_Q6 | 309 | 390 | 6.34E-08 | 1.98E-06 |
NGFIC_01 | 249 | 390 | 8.85E-08 | 2.60E-06 |
AP2_Q6 | 334 | 390 | 7.62E-07 | 2.00E-05 |
LRF_Q2 | 262 | 390 | 8.74E-07 | 2.18E-05 |
UF1H3BETA_Q6 | 20 | 390 | 8.70E-05 | 2.07E-03 |
AHRHIF_Q6 | 205 | 390 | 9.40E-05 | 2.10E-03 |
AHRARNT_02 | 195 | 390 | 1.99E-04 | 4.14E-03 |
MAZ_Q6 | 183 | 390 | 2.74E-04 | 5.48E-03 |
ZEC_01 | 2 | 390 | 3.48E-04 | 6.69E-03 |
TSA 24h | ||||
GC_01 | 161 | 194 | 1.45E-05 | 2.49E-03 |
NFY_01 | 118 | 194 | 9.66E-06 | 2.49E-03 |
E2F_Q2 | 141 | 194 | 4.78E-05 | 4.94E-03 |
SP1_Q2_01 | 143 | 194 | 8.48E-05 | 7.30E-03 |