From: RNA-Seq quantification of the human small airway epithelium transcriptome
Differentiated cell type | Gene symbol | Gene title | Expression level in SAE (RPKM)2 |
---|---|---|---|
Ciliated | TUBB2C | tubulin, beta 2C | 1161 |
 | ACTG1 | actin, gamma 1 | 513 |
 | TUBA1A | tubulin, alpha 1a | 342 |
 | HSPA1A | heat shock 70 kDa protein 1A | 266 |
 | HSPA1B | heat shock 70 kDa protein 1A///heat shock 70 kDa protein 1B | 260 |
 | TEKT2 | tektin 2 (testicular) | 146 |
 | DYNLT1 | dynein, light chain, Tctex-type 1 | 131 |
 | DNAI1 | dynein, axonemal, intermediate chain 1 | 108 |
 | DNALI1 | dynein, axonemal, light intermediate chain 1 | 108 |
 | DNAI2 | dynein, axonemal, intermediate chain 2 | 105 |
 | SPAG6 | sperm associated antigen 6 | 101 |
 | DYNLRB2 | dynein, light chain, roadblock-type 2 | 100 |
 | CROCC | ciliary rootlet coiled-coil, rootletin | 84 |
 | PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 73 |
 | DNAH9 | dynein, axonemal, heavy chain 9 | 63 |
 | CCDC146 | coiled-coil domain containing 146 | 60 |
 | RSPH4A | radial spoke head 4 homolog A (Chlamydomonas) | 59 |
 | CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 56 |
 | TCTEX1D2 | Tctex1 domain containing 2 | 50 |
 | IFT140 | intraflagellar transport 140 homolog (Chlamydomonas) | 49 |
Mucins and mucus components | AGR2 | anterior gradient homolog 2 | 166 |
 | TFF3 | trefoil factor 3 (intestinal) | 149 |
 | MUC1 | mucin 1, cell surface associated | 123 |
 | MUC5B | mucin 5B, oligomeric mucus/gel-forming | 118 |
 | MUC4 | mucin 4, cell surface associated | 93 |
 | MUC15 | mucin 15, cell surface associated | 28 |
 | MUC20 | mucin 20, cell surface associated | 27 |
 | MUC16 | mucin 16, cell surface associated | 20 |
 | MUC13 | mucin 13, cell surface associated | 15 |
 | MUCL1 | mucin-like 1 | 3.90 |
 | TFF1 | trefoil factor 1 | 2.09 |
 | PARM1 | prostate androgen-regulated mucin-like protein 1 | 1.85 |
 | EMR2 | egf-like module containing, mucin-like, hormone receptor-like 2 | 1.38 |
 | GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.81 |
 | MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.60 |
 | MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.58 |
 | MUC12 | mucin 12, cell surface associated | 0.46 |
Basal | MALAT1 | metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) | 461 |
 | CST3 | cystatin C | 295 |
 | PFN1 | profilin 1 | 224 |
 | ALDOA | aldolase A, fructose-bisphosphate | 183 |
 | SQSTM1 | sequestosome 1 | 106 |
 | MT2A | metallothionein 2A | 91 |
 | ENO1 | enolase 1, (alpha) | 89 |
 | KRT7 | keratin 7 | 83 |
 | MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric///myosin, light chain 12B, regulatory | 70 |
 | FLNB | filamin B, beta | 69 |
 | BRI3 | brain protein I3///hypothetical protein LOC644975 | 62 |
 | PLEC1 | plectin | 60 |
 | EIF5A | eukaryotic translation initiation factor 5A | 60 |
 | GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 57 |
 | KRT5 | keratin 5 | 54 |
 | PSMA7 | proteosome subunit alpha type 7 | 53 |
 | CTTN | cortactin | 52 |
 | JUP | junction plakoglobin | 51 |
 | MGST1 | microsomal glutathione S-trasnferase | 51 |
 | LMNA | laminin A | 49 |
Neuro- endocrine | ENO2 | enolase 2 (gamma, neuronal) | 23 |
 | GRP | gastrin-releasing peptide | 0.82 |
 | UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.65 |
 | SCG2 | secretogranin II | 0.48 |
 | ASCL1 | achaete-scute complex homolog 1 (Drosophila) | 0.34 |
 | CHGA | chromogranin A (parathyroid secretory protein 1) | 0.32 |