Skip to main content

Table 4 Performance of the classifier when the groups in which UniProt divides the protein kinase superfamily are considered individually

From: Prioritization of pathogenic mutations in the protein kinase superfamily

Group Accuracy (%) Precision (%) Recall (%) MCC
CMGC † 91.5 87.5 8.6 0.1
TKL † 68.7 70.5 70.9 0.4
TK † 71.3 69.7 68.3 0.4
RGC † 58.2 47.9 61.3 0.2
Atypical_PI3-PI4 † 70.6 47.1 100 0.8
STE 96.8 43.7 11.1 0.1
AGC † 90.8 43.3 61.1 0.5
Other 88.9 41.6 95.4 0.9
CK1 97.7 33.3 22.2 0.2
Atypical_Alpha-type 89.9 9.1 88.9 0.8
CAMK † 55.5 8.3 51.9 0.1
Atypical_ADCK 70.0 0 0 0
NEK 100 0 0 0
Atypical_RIO 100 0 0 0
Atypical_PDK-BCKDK 100 0 0 0
Atypical_FAST 100 0 0 0
  1. Performance of the classifier when the groups in which UniProt divides the protein kinase superfamily are considered individually. Groups enriched in disease-associated mutations are indicated by †.