| Â | MCC | Accuracy | Specificity | Sensitivity |
|---|
Global*
| 0.19 | 0.54 | 0.76 | 0.44 |
Minimum°
| 0.23 | 0.54 | 0.85 | 0.34 |
Maximum°
| 0.36 | 0.68 | 0.69 | 0.68 |
Average°
| 0.25 | 0.62 | 0.80 | 0.5 |
Random^
| 0.25 | 0.60 | 0.68 | 0.55 |
- *Global uses all data neglecting the correspondence between proteins and their conformers. °Minimum, Maximum and Average characterize the values of ΔΔG per SAS taking into account the conformers for each protein. ^Random MCC was calculated as an average over 50 independent selections of a randomly taken one ΔΔG value per SAS and per protein. In all the cases the threshold is ± 2kcal/mol. The difference between MCC values for Maximum and Random is significant at P-value=0.02. For definition of the different scoring indexes see text.
