Skip to main content

Table 2 Prediction of the disease type by protein similarity

From: Predicting cancer-associated germline variations in proteins

% Id

% prot

Sp(C)

Sp (N)

Sn (C)

Sn (N)

MCC

Q2

≤30

10

0.13

0.94

0.25

0.87

0.09

0.83

≤40

75

0.26

0.85

0.29

0.83

0.11

0.74

≤50

95

0.28

0.87

0.41

0.80

0.18

0.73

≤60

99

0.34

0.88

0.47

0.82

0.26

0.76

≤70

100

0.35

0.89

0.46

0.83

0.26

0.77

≤80

100

0.36

0.89

0.48

0.83

0.29

0.78

≤90

100

0.36

0.89

0.48

0.83

0.29

0.78

  1. %prot= percentage of proteins that can be annotated with a given similarity threshold cut-off. %Id= Threshold cut-off of the sequence identity of the best hit retrieved upon a BLAST search in our dataset. For a definition of classes and scoring indexes see section: Measuring the performance.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us