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Table 3 Prediction of the disease type by protein function

From: Predicting cancer-associated germline variations in proteins

GO sub-ontology % var Q MCC Sp(C) Sn(C) Sp(O) Sn(O)
C 89 0.76 0.3 0.58 0.34 0.79 0.91
F 98 0.77 0.45 0.83 0.39 0.75 0.96
P 96 0.89 0.63 0.79 0.62 0.9 0.96
CFP 100 0.75 0.52 0.40 0.97 0.99 0.71
  1. GO sub ontology: C=cellular component, F=molecular function, P=biological process. % var= percentage of predicted variations. Predicted classes: C= Cancer; O= Other genetic diseases. For a definition of classes and scoring indexes see section: Measuring the performance.
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