Table 5 Tamoxifen relevant proteins and their directionality
Drug | Protein | RpScore | Association | Direction |
|---|---|---|---|---|
Tamoxifen | AKT1_HUMAN | 82.99 | 1.77 | 1 |
Tamoxifen | BRCA2_HUMAN | 21.14 | 3.29 | 1 |
Tamoxifen | CADH1_HUMAN | 17.57 | 0.95 | 1 |
Tamoxifen | CDK2_HUMAN | 2.94 | 2.12 | 1 |
Tamoxifen | E2F1_HUMAN | 2.95 | 1.59 | 1 |
Tamoxifen | ERBB2_HUMAN | 2.07 | 3.19 | 1 |
Tamoxifen | ESR1_HUMAN | 72.39 | 5.11 | -1 |
Tamoxifen | IRS1_HUMAN | 2.51 | 1.29 | -1 |
Tamoxifen | JUN_HUMAN | 2.91 | 1.51 | 1 |
Tamoxifen | MYC_HUMAN | 3.49 | 2.5 | 1 |
Tamoxifen | NCOA3_HUMAN | 2.61 | 3.01 | -1 |
Tamoxifen | NCOR1_HUMAN | 2.81 | 4.05 | 1 |
Tamoxifen | P53_HUMAN | 169.82 | 0.8 | -1 |
Tamoxifen | P85A_HUMAN | 2.92 | 1.57 | 1 |
Tamoxifen | PTEN_HUMAN | 3.98 | 0.98 | 1 |
Plicamycin | MYC_HUMAN | 3.49 | 4.16 | -1 |
Plicamycin | SP1_HUMAN | 3.32 | 6.24 | -1 |