Table 4 RNAi resultant gene set overlapping cluster membership
From: Pathway Distiller - multisource biological pathway consolidation
Pathway Name, (enrichment p-value) | de novo Gene Membership | de novo Gene Ontology | de novo Protein Interactants | Weighted Consolidation | Enrichment Consolidation |
|---|---|---|---|---|---|
Base excision repair (p = 0.58) | ■ | ● | ■ | ■ | n/a |
Mismatch Repair (p = 0.75) | ■ | ● | ■ | ■ | n/a |
Homologous Recombination Repair (p = 0.73) | ■ | ■ | ■ | ■ | n/a |
DNA damage response (p = 0.09) | ■ | ■ | ■ | ■ | n/a |
Nucleotide Excision Repair (p = 1.99 × 10-4) | ■ | ■ | ■ | ▲ | ■ |
Proteasome (p = 3.4 × 10-3) | ■ | ■ | ■ | ► | ▲ |
Basal Transcription (p = 2.97 × 10-11) | ■ | ■ | ■ | ◄ | ► |
Ribosome (p = 6.65 × 10-3) | ■ | ■ | ■ | ♦ | ▼ |
TOR pathway (p = 2.90 × 10-3) | ▲ | ■ | ■ | ▼ | ● |
Notch Signaling Pathway (p = 3.05 × 10-4) | ▲ | ■ | ■ | ◘ | ◄ |
Glutathione Biosynthesis (p = 0.11) | ► | ► | ► | ● | n/a |