Table 5 HPD gene set overlapping cluster membership
From: Pathway Distiller - multisource biological pathway consolidation
Pathway Name, (enrichment p-value) | HPD similarity grouping | de novo Gene Membership | de novo Gene Ontology | de novo Protein Interactants | Weighted Consolidation | Enrichment Consolidation |
|---|---|---|---|---|---|---|
Aurora B signaling (p = 1.32 × 10-2) | ■ | ▲ | ■ | ▲ | ▲ | ■ |
Aurora A signaling (p = 1.39 × 10-4) | ■ | ■ | ■ | ■ | ■ | ■ |
Signaling by Aurora kinases (p = 3.27 × 10-4) | ■ | ■ | ■ | ■ | ■ | ■ |
FOXA transcription factor networks (p = 2.23 × 10-4) | ● | ● | ■ | ● | ● | ■ |
FOXA1 transcription factor network (p = 6.53 × 10-5) | ● | ● | ■ | ● | ● | ■ |
FOXA2 and FOXA3 transcription factor networks (p = 1.38 × 10-2) | ● | ● | ■ | ♦ | ♦ | ■ |
Fanconi Anemia pathway (p = 8.36 × 10-3) | ▲ | ▼ | ► | ► | ► | ■ |
ATRBRCA_PATHWAY (p = 6.75 × 10-3) | ▲ | ► | ► | ► | ► | ■ |
ATM mediated phosphorylation of repair proteins (p = 1.93 × 10-3) | ► | ► | ► | ▼ | ► | ■ |
Recruitment of repair and signaling proteins to double-strand breaks (p = 2.58 × 10-3) | ► | ► | ► | ▼ | ► | ■ |