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Table 2 Comparison of miRNA-centric μ and gene-centric ρ measuresa

From: MicroRNA-centric measurement improves functional enrichment analysis of co-expressed and differentially expressed microRNA clusters

GO terms ρ i ρ j ρ k ρ l p- value ρ (rank)
  μ i μ j μ k μ l p -value μ (rank)
GO:0033137, negative regulation 3 7485 0 10148 0.0765 (299)
of peptidyl-serine phosphorylation 6 0 282 265 0.0195 (14)
GO:0006474, N-terminal protein 3 7485 0 10148 0.0765 (299)
amino acid acetylation 6 0 320 227 0.0412 (28)
GO:0008054, cyclin catabolic 2 7486 2 10146 0.5668 (1842)
process 6 0 322 225 0.0427 (32)
GO:0031047, gene silencing by RNA 19 7460 6 10142 0.0006 (25)
  6 0 537 10 0.8958 (2566)
GO:0030335, positive regulation of cell migration 34 7454 16 10132 2.31e-04 (18)
  6 0 545 2 0.9783 (2879)
GO:0045944, positive regulation of 150 7338 112 10036 8.62e-07 (4)
transcription from RNA polymerase II promoter 6 0 546 1 0.9891 (2923)
GO:0006956, complement 1 7487 0 10148 0.4246 (1251)
activation 2 4 3 544 0.0010 (1)
GO:0060022, hard palate 1 7487 0 10148 0.4246 (1251)
development 4 2 85 462 0.0073 (3)
GO:0060123, regulation of growth 1 7487 0 10148 0.4246 (1251)
hormone secretion 4 2 87 460 0.0079 (4)
GO:0032926, negative regulation 3 7485 0 10148 0.07652 (286)
of activin receptor signaling pathway 5 1 226 321 0.0437 (35)
GO:0015936, coenzyme A 1 7487 1 10147 0.6689 (2086)
metabolic process 5 1 160 387 0.0102 (5)
  1. a The 'breast/up-regulated' miRNA cluster data from Volinia et al. (2006) using the target variation #6 (see Table 1) was used.