Figure 4

The 5p/3p arm selection of miR-324 and miR-455 in 10 breast cancer patients. (A) Ratios of 5p and 3p arms of miR-324 and miR-455 as observed from NGS data. (B) and (C) Ratios of 5p and 3p arms of miR-324 and miR-455 in the breast cancer tissues of 10 patients as evaluated using stem-loop quantitative PCR (left panels). Ratios of 5p and 3p arm usage are indicated in the boxplots in the right panels. All samples were assessed in triplicate and analyzed using Student's t test (p < 0.05 was considered significant)