The refractory cancer gene set interaction network annotated with the identified tissue type specificity. (I) Network built with contextual gene sets. Only 278 contextual gene sets with at least one interaction are shown. The contextual gene sets under-expressed across their corresponding contextual conditions are colored with green and over-expressed contextual gene sets are colored with red. (II) Network built with gene sets from ISA biclusters. Only 14 bicluster gene sets are shown with 10 identified interactions. No tissue type specificity was found in this network.