| hsa-miR- | |
---|
Protein | Total | 101 | 10a | 137 | 152 | 192 | 22 | 26a | 26b | 29b | 30b | 30c | 324- | 337 | 345 | 483 | 501 | 532 | 590 | 598 | 660 |
---|
| | | | | | | | | | | | 3p | | | | | | | | |
---|
CDK6
|
6
|
x
| |
x
| | |
x
|
x
|
x
|
x
| | | | | | | | | | | |
CTNNBIP1
|
5
| |
x
| | |
x
| |
x
|
x
|
x*
| | | | | | | | | | | |
AHSG |
4
| | | | | | | | |
x
| | |
x
| | | | |
x
| | |
x
|
HDAC4
|
4
| |
x
| | | |
x
| | |
x*
| | | | |
x
| | | | | | |
CHRD |
3
| | | | | |
x
| | | | | | |
x
| |
x
| | | | | |
COL1A1 |
3
| | | | | | |
x
|
x
|
x
| | | | | | | | | | | |
SOX2 |
3
| | | | | | |
x
|
x
| | | | | | | | | |
x
| | |
COL4A2 |
2
| | | | | | |
x
| |
x*
| | | | | | | | | | | |
DUSP2
|
2
| | | | | | | | |
x*
| | | | | | | | | | |
x
|
HIPK2 |
2
| | | | | | |
x
|
x
| | | | | | | | | | | | |
NOG |
2
| | | |
x
|
x
| | | | | | | | | | | | | | | |
SKI |
2
| | | | | | | | |
x
| | | | | | | | |
x
| | |
SMAD7 |
2
|
x
| | | | |
x
| | | | | | | | | | | | | | |
SOSTDC1 |
2
| | | | | | |
x
|
x
| | | | | | | | | | | | |
STATH |
2
|
x
| |
x
| | | | | | | | | | | | | | | | | |
TGFB3
|
2
| | | | |
x
| | | |
x*
| | | | | | | | | | | |
TOB1
|
2
| | | | | | |
x
|
x
| | | | | | | | | | | | |
ACVR2A |
1
| | | | |
x
| | | | | | | | | | | | | | | |
AREG |
1
| | | | | | | | | | | | | |
x
| | | | | | |
COL5A3 |
1
| | | | | | | | |
x
| | | | | | | | | | | |
SMAD6
|
1
| | | | | | | | |
x
| | | | | | | | | | | |
- Bioinformatic target predictions for the subset of 20 miRNAs upregulated in osteogenic differentiation of USSC on osteo-inhibitory proteins: miR-26a, -26b, and -29b were experimentally assessed for impact on proteins denoted in bold. The second column (“Total”) illustrates the number of miRNAs from the analyzed set that targets an individual protein. Predictions with an asterix were already validated in the literature.