Figure 3
Expression patterns of CP genes through palatal stages: FPKM values of each CP gene were transformed into log 10 (FPKM + 1) and rounded up to 2 decimal places. These 322 CP genes were categorized into 9 possible expression patterns (p) based on the comparison of the transformed FPKM values with FC ≥ 2.0 across 3 different gestational groups for each genotype (n = 3). The patterns represent the expression value of the transcript first from E14.5 to E15.5, then from E15.5 to E16.5. Each pattern is color-coded to differentiate patterns for further analysis. p1 unchanged-unchanged (remain unchanged); p2 upregulated-unchanged; p3 unchanged-upregulated; p4 upregulated-downregulated; p5 upregulated-upregulated; p6 downregulated-unchanged; p7 downregulated-upregulated; p8 unchanged-downregulated; and p9 downregulated-downregulated.