MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells

BMC Genomics

Table 2 Putative targets of miR-30a after whole genome expression (WGE) analysis of miR-30a overexpression

Gene name	Pre-miR-30a	miR-159 k.d.	Fold-change	Score
*ACP2*	103.98	160.67	0.65	−6.23
*ARID5B*	97.55	145.53	0.67	−2.96
*ARVCF*	44.57	61.42	0.73	−2.66
*ATG12*	134.92	192.78	0.70	−3.36
*AVEN*	89.8	166.93	0.54	−9.51
*BNIP3L*	64.7	95.14	0.68	−4.93
*C14orf129*	165.21	278.97	0.59	−1.92
*C1orf19*	291.73	475.23	0.61	−11.7
*C2orf30*	175.86	317.2	0.55	−10.18
*C3orf57*	855.03	1500.97	0.57	−1.39
*CHMP2B*	294.63	447.1	0.66	−7.54
*DCUN1D3*	85.59	141.19	0.61	1.38
*DPY19L1*	194.24	277.5	0.70	−4.87
*DPYSL2*	315.4	502.3	0.63	−5.31
*EDG3*	100.43	149.23	0.67	−1.99
*ELMOD2*	81.24	123.28	0.66	1.74
*FAM18B*	121.66	169.09	0.72	−4.05
*FOXD1*	104.98	150.49	0.70	−2.49
*GNAI2*	229.93	496.33	0.46	−11.2
*GNG10*	91.32	139	0.66	−7.76
*GNPDA1*	489.02	831.37	0.59	−0.6
*KDELC2*	116.08	204.6	0.57	−3.39
*KIAA0241*	99.59	151.45	0.66	−2.69
*NECAP1*	157.52	253.56	0.62	−6.58
*PDSS1*	257.51	381.04	0.68	5.63
*PGM1*	196.55	309.58	0.63	−6.5
*PIK3R2*	762.04	1060.6	0.72	−5.76
*PPP1R2*	279.79	504.81	0.55	−9.54
*REEP3*	56.69	79.57	0.71	−5.93
*REXO4*	174.68	257.94	0.68	−6.87
*RPA2*	385.11	641.74	0.60	−1.52
*SEC23A*	54.91	75.17	0.73	−4.48
*TFDP1*	709.63	1059.53	0.67	−7.84
*TM4SF1*	436.61	828.33	0.53	−6.84
*TRIB3*	277.11	422.9	0.66	−2.06
*VKORC1L1*	335.84	525.07	0.64	−3.44

Significantly downregulated genes after Pre-miR-30a transfection. Only potential targets with 3′UTR seed sequences of miR-30a are included. “Scores” are based on the PITA algorithm, as described in Materials and Methods. Targets common to miR-30 family WGE analysis are underlined.

ISSN: 1471-2164