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Table 4 Relative mRNA expression of experimental treatments at 3 hr for genes involved in adherin junctions, tight junctions, or angiogenesis

From: Comparison of the global gene expression of choroid plexus and meninges and associated vasculature under control conditions and after pronounced hyperthermia or amphetamine toxicity

NCBI gene symbol

AMPH compared to control

EIH compared to control

AMPH compared to EIH

 

MAV

Choroid plexus

MAV

Choroid plexus

MAV

Choroid plexus

Ocln

0.36

1.17a

0.67

1.21a

0.54

0.96a

Cldn1

0.86

1.04a

0.97

1.18a

0.88

0.88a

Cldn3

1.22

1.02

0.99

0.88

1.23

1.16

Cldn4

1.50

0.77

1.60

1.00

0.94

0.78

Cldn5

0.41 a

0.32

0.59a

0.48

0.69a

0.66

Cldn11

0.88

0.48

0.81

0.77

1.09

0.62

Magi2

0.90

0.51

1.16

0.88

0.77

0.58

Magi3

0.74

1.01

1.08

1.07

0.69

0.94

Esam

2.07 b

1.92

1.14

1.85

1.85a

1.04

F11r (Jam1)

0.73a

1.09

0.69a

0.94

1.06a

1.16

Jam2

0.67

0.97

0.96

0.92

0.70

1.05

Jam3

0.77

0.77

0.84

0.71

0.91

1.09

Cdh5

0.92

0.87

1.03

1.41

0.90

0.62

Aqp4

0.76a

0.52

1.05b

0.66

0.73a

0.78

Slc2a1

1.39

0.82

1.13

1.04

1.24

0.79

Angpt2

1.02a

1.12

1.02a

1.21

1.00a

0.66

Tek

0.43

0.88

0.62

1.38

0.69

0.64

Ctnnb1

1.29

0.74

0.83

0.68

1.56

1.09

Pdgfrb

0.60

0.60

0.86

0.95

0.70

0.63

Sox18

0.33 a

0.70

0.67a

0.70

0.50a

1.01

Agrn

0.70

0.81

0.77

0.70

0.91

1.15

  1. Bold text indicates genes that were significantly differentially expressed (FDR = 0.10) between treatment comparisons.
  2. a Array expression results were confirmed with RT-PCR.
  3. b Array expression results were not confirmed with RT-PCR.