Figure 3

Targeted degradation of S.erythraea transcriptome. (A) Heat map summarising relative expression profile of annotated ribonucleases. Ribonuclease expression profile across the growth cycle shows a collective induction at the switch coinciding with RNA degradation observed at the switch. (B) Box-whisker plot (Tukey distribution, n = 24) summarising relative fold enrichment of ribonuclease expression across the metabolic switch. (C) Bioanalyzer tracer showing RNA quality sampled across the S.erythraea fermentation cycle. RNA shows smeared RNA degradation at switch (arrow) correlating with high RNAse activity.