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Table 4 Candidate genes in the epistatic QTL regions and their involvement in growth-related pathways

From: Genetic dissection of growth traits in a Chinese indigenous × commercial broiler chicken cross

Trait Gene Chr Position bp/(cM)1 Pathway2
BW6 UBE2A ubiquitin-conjugating enzyme E2A 4 16506437 – 16512992 (55–55.1) UMP
MARCH7 membrane-associated ring finger (C3HC4) 7 7 36187561 – 36207776 (99.8) UMP
GR 48 HERC4 hect domain and RLD 4 6 10024961 – 10054292 (36.7) UMP
ZBTB1 zinc finger and BTB domain containing 1 5 52791938 – 52805593 (135.1) UMP
MID1 midline 1 1 124042084-124134384 (296.9) UMP
FCR 68 RNF144A ring finger protein 144A 3 94598486 – 94657682 (206.8) UMP
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 26 3847830 – 3854232 (43.6) ER
FCR 810 ITCH itchy E3 ubiquitin protein ligase homolog 20 1769346 – 1829955 (7.5–7.7) UMP
TGFA Transforming growth factor alpha 22 3012283 – 3020403 (41.1) ER
  1. 1 The physical locations of the genes based on the WASHUC 3.1 build, and the genetic locations of the scored SNP markers located within the gene. 2 UMP: Ubiquitin-mediated proteolysis; ER: ErbB signalling.