Figure 2

Both physiologic and genotoxic damage initiate a lymphocyte-specific maturation gene expression response. (A) Fold change from the microarray analysis of representative common genes. (B) Some of the significant IPA canonical pathways representing the 288 common probes (pathway significance bar at p-value = 0.01). (C) Flow cytometric analysis of CD40 protein expression on STI-571 treated WT cells 90 minutes following exposure to 0 Gy or 1 Gy IR.