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Figure 2 | BMC Genomics

Figure 2

From: A kinetic model of the evolution of a protein interaction network

Figure 2

The kinetic model of the protein interactome evolution. a. Schematic representation of proteome formation. b. Schematic representation of interactome formation. The symbols X and Y indicate the protein class. Other symbols indicate rates: f 0 - protein origination, k i - protein inactivation, k XY and k YX - protein transition between classes, k 2 - protein duplication, f0ξ0/N - emergence of an interaction with a newborn protein, μ emergence of an interaction with an existing protein, Δμ- preference and r – loss of interaction.

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