Members in the CYP6BQ cluster. (A) Neighbor-joining tree of the cluster CYP6BQ genes. The sequences of CYP6BQ8, CYP6BQ9, CYP6BQ10, and CYP6BQ11 were cloned from QTC279 strain (Pyr), GA strain and LA strain as described in the Methods. (B) Tissue specific expression profile of the cluster CYP6BQ genes in the deltamethrinresistant QTC279 strain. The rectangles are colored on the basis of results of relative expression levels compared with that of ovary and normalized by the expression of rp49. The data shown are mean + SEM (n = 3). The levels of relative expression are illustrated by a four- category color scale standing for 0-1, 1-10, 10-100, >100 fold, respectively.