Gene ID | Protein name | EC number | Biological process/molecular function | aFold change of oocyst vs tachyzoite mRNA levels | Protein probability | ||
---|---|---|---|---|---|---|---|
 |  |  |  | day 0 | day 4 | day 10 |  |
energy | Â | Â | Â | Â | Â | Â | Â |
TGME49_026300 | oxidoreductase, putative | 1.3.1.34 | fatty acid β-oxidation | 260 | 40 | 103 | 6.23E-11 |
TGME49_034570 | peroxisomal multifunctional enzyme type 2, putative | 1.1.1.35 | fatty acid β-oxidation | 108 | 12 | 17 | 2.22E-16 |
TGME49_042390 | enoyl-CoA hydratase/isomerase family protein, putative | 4.2.1.17 | fatty acid β-oxidation | 21 | 16 | 5 | 1.35E-12 |
TGME49_047500 | acyl-coenzyme A oxidase, putative | 1.3.3.36 | fatty acid β-oxidation | 92 | 37 | 49 | 6.76E-12 |
TGME49_066270 | 2-methylbutyryl-CoA dehydrogenase, putative | 1.3.99.- | fatty acid β-oxidation | 7 | <2 | <2 | 1.00E-30 |
TGME49_115480 | acyl-CoA oxidase, putative | 1.3.3.36 | fatty acid β-oxidation | 183 | 71 | 151 | 1.91E-10 |
TGME49_032580 | acetyl-coenzyme A synthetase, putative | 6.2.1.1 | glycolysis/gluconeogenesis | 43 | 5 | 12 | 1.00E-30 |
TGME49_089930 | phosphoenolpyruvate carboxykinase, putative | 4.1.1.49 | glycolysis/gluconeogenesis | 30 | 3 | 6 | 8.70E-07 |
TGME49_016090 | tropomyosin 1 alpha chain, putative | - | regulation of actin mechanics | 247 | 11 | 19 | 5.66E-06 |
TGME49_027050 | pyruvate dehydrogenase kinase, putative | 2.7.11.2 | regulation of pyruvate dehydrogenase | 3 | 4 | 3 | 2.16E-07 |
TGME49_071210 | 4-alpha-glucanotransferase, putative | 2.4.1.25/3.2.1.33 | starch and glucose metabolism | 5 | 254 | 26 | 1.11E-15 |
TGME49_003110 | citrate synthase, putative | 2.3.3.1 | TCA cycle | 35 | 5 | 7 | 6.32E-09 |
metabolism | Â | Â | Â | Â | Â | Â | Â |
TGME49_003340 | alkyl sulfatase, putative | 3.5.2.6 | - | 8 | <2 | 2 | 2.10E-05 |
TGME49_003580 | NAD-binding domain-containing protein | - | - | n.a. | n.a. | n.a. | 4.73E-12 |
TGME49_038200 | alpha/beta hydrolase fold domain containing protein | - | - | 27 | 3 | 4 | 7.77E-15 |
TGME49_065860 | nit protein 2, putative | - | - | 5 | <2 | <2 | 2.74E-11 |
TGME49_069120 | oxidoreductase, putative | 1.1.1.100 | - | 183 | 61 | 125 | 4.44E-16 |
TGME49_069400 | short chain dehydrogenase/reductase domain-containing protein | 1.1.1.100 | - | 11 | <2 | <2 | 2.42E-07 |
TGME49_106450 | short chain dehydrogenase family protein, putative | 1.1.1.100 | - | <2 | 222 | 82 | 6.97E-05 |
TGME49_111780 | alcohol dehydrogenase class III, putative | 1.1.1.284 | - | 4 | <2 | <2 | 4.61E-06 |
TGME49_003500 | alanine dehydrogenase, putative | 1.4.1.1 | amino acid metabolism | 6 | 29 | 4 | 1.11E-15 |
TGME49_005420 | aspartate-semialdehyde dehydrogenase, putative | 1.2.1.11 | amino acid metabolism | 4 | <2 | <2 | 2.44E-08 |
TGME49_016640 | homoserine kinase, putative | 2.7.1.39 | amino acid metabolism | 74 | 28 | 26 | 4.03E-12 |
TGME49_059180 | cystathionine beta-synthase, putative | 4.2.1.22 | amino acid metabolism | n.a. | n.a. | n.a. | 8.37E-13 |
TGME49_069110 | ornithine aminotransferase, putative | 2.6.1.13 | amino acid metabolism | 394 | 123 | 247 | 2.54E-12 |
TGME49_078910 | O-acetylserine (thiol) lyase, putative | 2.5.1.47 | amino acid metabolism | 20 | 3 | 5 | 2.39E-10 |
TGME49_112930 | cystathionine beta-lyase, putative | 4.4.1.1 | amino acid metabolism | 23 | 2 | 3 | 2.90E-10 |
TGME49_115260 | alanine dehydrogenase, putative | 1.4.1.1 | amino acid metabolism | 98 | 211 | 331 | 2.89E-14 |
TGME49_019230 | acetoacetyl-CoA synthetase, putative | 6.2.1.16 | butanoate metabolism | <2 | <2 | <2 | 4.97E-10 |
TGME49_031900 | acyl-CoA dehydrogenase, putative | 1.3.99.7 | fatty acid metabolism | 31 | 32 | 21 | 6.51E-11 |
TGME49_003570 | acyltransferase, putative | 2.3.1.15 | glycerophospholipid metabolism | 2 | <2 | <2 | 3.08E-13 |
TGME49_010260 | glycerol-3-phosphate dehydrogenase, putative | 1.1.1.8 | glycerophospholipid metabolism | 188 | 14 | 32 | 6.84E-13 |
TGME49_082230 | sulfate adenylyltransferas-adenylylsulfate kinase, putative | 2.7.7.4 | purine metabolism | 52 | 5 | 10 | 7.38E-13 |
TGME49_107030 | purine nucleoside phosphorylase | 2.4.2.3 | pyrimidine salvage pathway | 12 | 2 | 3 | 1.11E-16 |
TGME49_003720 | vitamin K epoxide reductase complex subunit 1, putative | 1.1.4.1 | terpenoid-quinone biosynthesis | 9 | 21 | 23 | 1.63E-08 |
TGME49_002140 | methylglutaconyl-CoA hydratase, putative | 4.2.1.18 | valine, leucine and isoleucine degradation | 5 | 2 | 2 | 1.02E-06 |
TGME49_005430 | isovaleryl-CoA dehydrogenase, putative | 1.3.99.10 | valine, leucine and isoleucine degradation | 8 | 13 | 6 | 2.49E-10 |
TGME49_015250 | thiamin pyrophosphokinase, putative | 2.7.6.2 | vitamin biosynthesis | <2 | <2 | <2 | 1.03E-09 |
cell rescue, defence and virulence | Â | Â | Â | Â | Â | Â | Â |
TGME49_005660 | F5/8 type C domain-containing protein (CCp1A) | - | - | 114 | 11 | 14 | 1.00E-30 |
TGME49_023480 | thrombospondin type 1 domain-containing protein | - | - | 24 | <2 | <2 | 6.35E-07 |
TGME49_056040 | LCCL domain-containing protein (CCp5B) | - | - | 343 | 24 | 32 | 1.11E-15 |
TGME49_058370 | Rhoptry kinase family protein ROP28 | - | - | <2 | 46 | 23 | 2.51E-12 |
TGME49_063410 | scavenger receptor protein TgSR2 | - | - | 144 | 12 | 12 | 2.22E-15 |
TGME49_064070 | antigenic protein, putative (CCp1B) | - | - | 76 | 7 | 8 | 1.10E-10 |
TGME49_067410 | scavenger receptor protein TgSR1 | - | - | 306 | 26 | 29 | 2.21E-08 |
TGME49_027150 | glutaredoxin, putative | - | detoxification of oxygen radicals | -3 | -3 | -3 | 6.84E-05 |
TGME49_116190 | superoxide dismutase, putative | 1.15.1.1 | detoxification of oxygen radicals | <2 | 589 | 470 | 3.76E-12 |
TGME49_009920 | PAN domain-containing protein | - | host cell attachment/invasion | <2 | 557 | 142 | 2.33E-14 |
TGME49_032400 | PAN domain-containing protein | - | host cell attachment/invasion | <2 | 44 | 8 | 7.77E-15 |
TGME49_038460 | SRS22B | - | host cell attachment/invasion | <2 | <2 | <2 | 8.95E-05 |
TGME49_058550 | SRS28 (SporoSAG) | - | host cell attachment/invasion | 2 | 323 | 312 | 1.44E-14 |
TGME49_058810 | SRS27B | - | host cell attachment/invasion | <2 | 153 | 46 | 4.84E-09 |
TGME49_065120 | hypothetical protein, conserved (RON2 iso2) | - | moving junction formation | <2 | 28 | 13 | 8.17E-08 |
TGME49_094400 | hypothetical protein (RON2 iso 1) | - | moving junction formation | n.a. | n.a. | n.a. | 5.89E-06 |
TGME49_115730 | apical membrane antigen, putative (AMA1 iso1) | - | moving junction formation | <2 | 16 | 4 | 4.98E-12 |
cell cycle and DNA processing | Â | Â | Â | Â | Â | Â | Â |
TGME49_006400 | DNA photolyase, putative | 4.1.99.3 | DNA repair | 34 | 252 | 99 | 1.82E-10 |
protein fate | Â | Â | Â | Â | Â | Â | Â |
TGME49_016150 | oligoendopeptidase F, putative | - | - | 213 | 25 | 52 | 1.21E-11 |
TGME49_031060 | subtilase family serine protease, putative | 3.4.21.66 | - | <2 | 2 | <2 | 3.95E-07 |
TGME49_034950 | protein kinase (incomplete catalytic triad) | - | - | <2 | 2 | 5 | 2.22E-15 |
TGME49_044620 | NEK kinase | 2.7.12.2 | - | 2 | <2 | <2 | 1.11E-10 |
TGME49_046800 | acylamino-acid-releasing enzyme, putative | 3.4.19.1 | - | <2 | -2 | <2 | 2.10E-10 |
TGME49_047240 | ubiquitin carboxyl-terminal hydrolase isozyme L5, putative | 3.4.19.12 | deubiquitination pathway | 3 | -2 | <2 | 7.70E-11 |
TGME49_066780 | protein kinase (incomplete catalytic triad) | - | - | 3 | <2 | <2 | 4.22E-14 |
TGME49_089240 | DnaJ domain-containing protein | 1.3.1.38 | - | <2 | <2 | <2 | 4.52E-11 |
TGME49_095640 | endothelin-converting enzyme, putative | 3.4.24.71 | - | 27 | 3 | 4 | 3.79E-12 |
TGME49_107640 | CMGC kinase, CK2 family | 2.7.12.2 | - | 140 | 19 | 27 | 2.15E-12 |
TGVEG_058750 | protein kinase domain-containing protein, putative | 2.7.11.11 | - | n.a. | n.a. | n.a. | 8.47E-07 |
cellular transport, transport facilities and transport routes | Â | Â | Â | Â | Â | Â | Â |
TGME49_065230 | electron transfer flavoprotein-ubiquinone oxidoreductase, putative | 1.5.5.1 | - | 8 | 3 | 3 | 1.13E-12 |
TGME49_114330 | ABC transporter, putative | 3.6.3.44 | - | 31 | 13 | 12 | 9.50E-05 |
protein synthesis | Â | Â | Â | Â | Â | Â | Â |
TGME49_020300 | ribosomal protein L15, putative | - | translation | <2 | <2 | <2 | 9.08E-05 |
biogenesis of cellular components | Â | Â | Â | Â | Â | Â | Â |
TGME49_043720 | peroxisomal biogenesis factor 11 domain-containing protein | - | peroxisome fission | 15 | 22 | 20 | 1.25E-05 |
TGME49_086250 | oocyst wall protein, putative (OWP6) | - | oocyst environmental resistance | 44 | 7 | 12 | 6.83E-10 |
other | Â | Â | Â | Â | Â | Â | Â |
TGGT1_064840 | hypothetical protein | - | - | n.a. | n.a. | n.a. | 7.85E-08 |
TGGT1_071710 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 5.11E-12 |
TGGT1_090830 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 2.89E-05 |
TGGT1_099390 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 7.99E-14 |
TGGT1_122010 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 6.77E-14 |
TGGT1_122320 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 4.09E-13 |
TGME49_002100 | hypothetical protein | - | - | 847 | 425 | 583 | 1.36E-07 |
TGME49_002110 | hypothetical protein | - | - | 1163 | 321 | 751 | 7.05E-11 |
TGME49_003230 | hypothetical protein | - | - | 11 | 42 | 27 | 3.05E-09 |
TGME49_003890 | hypothetical protein | - | - | 29 | 150 | 77 | 1.80E-09 |
TGME49_007250 | hypothetical protein | - | - | 155 | 15 | 28 | 7.55E-07 |
TGME49_009470 | hypothetical protein | - | - | 476 | 63 | 155 | 7.17E-10 |
TGME49_009810 | hypothetical protein | - | - | <2 | 30 | 11 | 2.86E-12 |
TGME49_012030 | hypothetical protein | - | - | <2 | 9 | 5 | 8.40E-11 |
TGME49_016970 | hypothetical protein, conserved | - | - | -5 | 2 | <2 | 1.44E-14 |
TGME49_020280 | SCP-like domain-containing protein | - | - | n.a. | n.a. | n.a. | 1.00E-30 |
TGME49_023430 | hypothetical protein | - | - | <2 | 66 | 6 | 1.23E-09 |
TGME49_023830 | fasciclin domain-containing protein | - | - | n.a. | n.a. | n.a. | 1.50E-08 |
TGME49_023900 | hypothetical protein | - | - | 4 | <2 | <2 | 4.63E-05 |
TGME49_025120 | rRNA processing protein, putative | - | - | n.a. | n.a. | n.a. | 1.00E-09 |
TGME49_026230 | hypothetical protein | - | - | <2 | 21 | 21 | 3.78E-08 |
TGME49_028240 | hypothetical protein | - | - | <2 | <2 | <2 | 2.11E-13 |
TGME49_030530 | hypothetical protein | - | - | 220 | 22 | 33 | 1.99E-10 |
TGME49_030540 | hypothetical protein | - | - | 53 | 6 | 10 | 4.33E-08 |
TGME49_031390 | hypothetical protein | - | - | 618 | 69 | 138 | 1.46E-09 |
TGME49_037080 | hypothetical protein | - | - | 1315 | 582 | 905 | 1.56E-10 |
TGME49_038160 | hypothetical protein | - | - | <2 | 252 | 78 | 1.03E-13 |
TGME49_038910 | hypothetical protein | - | - | n.a. | n.a. | n.a. | 3.50E-05 |
TGME49_040610 | hypothetical protein, conserved | - | - | 65 | 5 | 3 | 3.57E-08 |
TGME49_044410 | hypothetical protein | - | - | n.a. | n.a. | n.a. | 1.67E-07 |
TGME49_048170 | hypothetical protein | - | - | <2 | 4 | 2 | 3.33E-14 |
TGME49_048230 | hypothetical protein | - | - | <2 | <2 | <2 | 7.93E-05 |
TGME49_054760 | hypothetical protein | - | - | 153 | 126 | 80 | 1.12E-07 |
TGME49_055380 | hypothetical protein | - | - | 917 | 150 | 228 | 8.39E-12 |
TGME49_057690 | hypothetical protein | - | - | 16 | 3 | 3 | 2.10E-10 |
TGME49_058200 | glutamic acid-rich protein, putative | - | - | <2 | 48 | 31 | 6.43E-09 |
TGME49_058380 | hypothetical protein | - | - | <2 | <2 | <2 | 6.17E-05 |
TGME49_059670 | von Willebrand factor type A domain-containing protein | - | - | <2 | 257 | 41 | 2.22E-15 |
TGME49_062470 | beta antigen, putative | - | - | 658 | 129 | 203 | 5.09E-05 |
TGME49_065130 | hypothetical protein | - | - | <2 | <2 | <2 | 3.30E-11 |
TGME49_067980 | hypothetical protein | - | - | <2 | 9 | 5 | 2.01E-07 |
TGME49_068880 | hypothetical protein | - | - | -19 | -3 | -4 | 3.51E-09 |
TGME49_069350 | hypothetical protein | - | - | <2 | <2 | <2 | 3.29E-11 |
TGME49_070950 | hypothetical protein | - | - | 15 | 238 | 348 | 5.74E-08 |
TGME49_071490 | hypothetical protein | - | - | 198 | 148 | 282 | 6.91E-13 |
TGME49_073510 | hypothetical protein | - | - | <2 | 79 | 41 | 6.66E-15 |
TGME49_073670 | hypothetical protein | - | - | -2 | <2 | <2 | 3.79E-05 |
TGME49_073700 | hypothetical protein | - | - | 260 | 27 | 52 | 3.42E-08 |
TGME49_076860 | late embryogenesis abundant domain-containing protein | - | - | <2 | 556 | 390 | 2.22E-15 |
TGME49_076870 | LEA1 protein, putative | - | - | 8 | 497 | 146 | 2.03E-12 |
TGME49_078120 | SCP-like extracellular domain-containing protein | - | - | <2 | 96 | 66 | 5.81E-09 |
TGME49_078340 | hypothetical protein | - | - | 2 | 4 | <2 | 6.67E-07 |
TGME49_079440 | hypothetical protein, conserved | - | - | 161 | 14 | 26 | 4.43E-09 |
TGME49_080430 | hypothetical protein | - | - | 1057 | 220 | 376 | 1.47E-07 |
TGME49_085690 | notch (DSL) domain-containing protein | - | - | 121 | 15 | 21 | 8.51E-12 |
TGME49_087840 | hypothetical protein | - | - | <2 | <2 | <2 | 3.00E-14 |
TGME49_088220 | hypothetical protein | - | - | 52 | 51 | 13 | 1.00E-30 |
TGME49_089740 | hypothetical protein | - | - | <2 | -4 | <2 | 3.44E-07 |
TGME49_090610 | hypothetical protein | - | - | 557 | 38 | 42 | 5.26E-08 |
TGME49_091840 | hypothetical protein | - | - | 260 | 15 | 26 | 1.00E-30 |
TGME49_093780 | hypothetical protein | - | - | -60 | <2 | <2 | 2.56E-06 |
TGME49_094600 | hypothetical protein | - | - | 15 | 506 | 557 | 3.19E-13 |
TGME49_097280 | hypothetical protein, conserved | - | - | <2 | 453 | 139 | 2.63E-13 |
TGME49_097410 | hypothetical protein | - | - | 187 | 31 | 72 | 1.38E-08 |
TGME49_106050 | hypothetical protein | - | - | 89 | 14 | 30 | 1.11E-15 |
TGME49_106500 | hypothetical protein | - | - | <2 | <2 | <2 | 6.28E-11 |
TGME49_109530 | hypothetical protein | - | - | <2 | 3 | <2 | 1.96E-11 |
TGME49_109540 | hypothetical protein | - | - | <2 | <2 | <2 | 2.57E-10 |
TGME49_110160 | piwi-PAZ domain-containing protein (TgAgo) | - | gene silencing | 21 | 7 | 5 | 7.45E-12 |
TGME49_116890 | hypothetical protein | - | - | 46 | 5 | 9 | 5.18E-12 |
TGME49_119890 | hypothetical protein | - | - | -14 | 53 | 33 | 1.08E-09 |
TGME49_120280 | hypothetical protein | - | - | 3 | 16 | 12 | 7.52E-12 |
TGME49_120290 | hypothetical protein | - | - | 8 | <2 | <2 | 4.68E-11 |
TGME49_120500 | patched transmembrane domain-containing protein | - | - | 12 | <2 | <2 | 1.37E-07 |
TGME49_120710 | hypothetical protein | - | - | <2 | 9 | 4 | 2.15E-07 |
TGVEG_029770 | hypothetical protein | - | - | n.a. | n.a. | n.a. | 6.87E-06 |
TGVEG_051660 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 8.83E-13 |
TGVEG_058740 | hypothetical protein, conserved | - | - | n.a. | n.a. | n.a. | 2.22E-16 |
TGVEG_060360 | hypothetical protein | - | - | n.a. | n.a. | n.a. | 1.28E-11 |
TGVEG_095590 | hypothetical protein | - | - | n.a. | n.a. | n.a. | 3.27E-11 |