Transcriptional analysis of the three Nlrp1 paralogs in mice

BMC Genomics

Table 2 Expression profile of Nlrp1a , Nlrp1b (splice) variants, and Nlrp1c

Mouse strain	Nlrp1a	Nlrp1b(SV1, SV2)	Nlrp1b(all other variants)	Nlrp1c
BALB/cJ	-	-	+	-
SWR/J	-	-	+	-
FVB/J	-	-	+	-
129S1/SvlmJ	-	-	+	-
C57BL/6Tac Nlrp ^S/S	-	-	+	-
C57/LJ	-	-	+	-
CAST/EiJ	+	+	+	-
C57BL/6J	+	+	+	+
A/J	+	+	+	+
I/LnJ	+	+	+	+
C57BL/6Tac Nlrp^R/R	+	+	+	+
AKR/J	+	-	+	-
NOD/LtJ	+	-	+	-
DBA/2J	+	-	+	-
PWD/PhJ	+	+	+	+
PWK/PhJ	+	+	+	+
SPRET/EiJ	+	-	-	-
129S1/SvmlJ Nlrp^−/−	-	-	-	-

Mouse strain names written in bold letters indicate that they harbor lethal toxin sensitive macrophages. +/− refers to presence or absence of PCR product.

ISSN: 1471-2164