Table 1 The eQTL hotspots and their candidate regulators from GFlasso and other previous analyses
eQTL Hotspot | eQTL module size | cisgenes in eQTL module GFlasso | Yvert et al. [17] | Zhu et al. [9] | Lee et al. [8] |
|---|---|---|---|---|---|
*II:380000 | 106 | NRG1 TIP1 TAT1 TEC1 ECM33 | none | none | RDH54 SEC18 SPT7 |
*II:560000 | 722 | AMN1 MAK5 CNS1 TBs1 TOS1 ARA1 SUP45 CSH1 RPB5 SDS24 ENP1 REI1 | AMN1 MAK5 | AMN1 CNS1 TBS1 TOS1 ARA1 SUP45 CSH1 | AMN1 CNS1 TOS2 ABD1 PRP5 TRS20 |
*III:100000 | 225 | LEU2 ILV6 NFS1 CIT2 PGS1 RER1 HIS4 FRM2 KCC4 | LEU2 | LEU2 ILV6 NFS1 CIT2 MATALPHA1 | LEU2 ILV6 PGS1 |
*III:200000 | 62 | MATALPHA1 MATALPHA2 PHO87 BUD5 TAF2 | MATALPHA1 | MATALPHA1 | MATALPHA1 MATALPHA2 TBK1 |
IV:1500000 | 46 | YRF1-1 YDR539W YDR541C | - | - | - |
*V:110000 | 45 | URA3 NPP2 | URA3 | URA3 | URA3 NPP2 PAC2 |
V:350000 | 618 | RPS24A RPS8B RTT105 | - | - | - |
V:420000 | 405 | LCP5 NSA2 | - | - | - |
V:460000 | 42 | YER138C UBP5 RTR1 | - | - | - |
VII:50000 | 350 | RAI1 TAD1 KAP114 | - | - | - |
*VIII:110000 | 147 | GPA1 YAP3 ERG11 LAG1 SHO1 ETP1 YLF2 LEU5 | GPA1 | GPA1 | GPA1 STP2 NEM1 |
X:20000 | 48 | YJL225C VTH2 FSP2 REE1 | - | - | - |
XII:610000 | 53 | TOP3 | - | - | - |
*XII:680000 | 185 | HAP1 NEJ1 SSP120 | HAP1 | HAP1 | HAP1 NEJ1 GSY2 |
XII:780000 | 44 | REC102 PEX30 FKS1 GAS2 | - | - | - |
*XII:1070000 | 54 | YRF1-4 YRF1-5 YLR464W YLR462W | SIR3 | YRF1-4 YRF1-5 YLR464W | SIR3 HMG2 ECM7 |
*XII:70000 | 76 | MDM1 | none | none | ARG81 TAF13 CAC2 |
*XIV:490000 | 448 | SAL1 TOP2 MKT1 THO2 MSK1 TPM1 LAT1 SWS2 | none | SAL1 TOP2 | TOP2 MKT1 MSK1 |
XIV:550000 | 45 | COG6 YIP3 HDA1 | - | - | - |
XV:90000 | 85 | ZEO1 RFC4 HM11 INO4 NDJ1 SKM1 HAL9 | - | - | - |
*XV:180000 | 406 | PHM7 ATG19 WRS1 RFC4 | none | PHM7 | PHM7 ATG19 BRX1 |
*XV:59000 | 120 | LSC1 YOR131C RAS1 INP53 OST2 PIN2 | CAT5 | none | CAT5 ADE2 ORT1 |