Figure 5

Multiple components of the visual transduction cascade are rhythmically expressed and in similar phases in both An. gambiae and Ae. aegypti.(A) Mosquito homologues to genes in the Drosophila phototransduction cascade signaling complex were identified as rhythmic in LD heads using the JTK_CYCLE algorithm (q < 0.05). Peak phase in expression is indicated next to gene names as Zeitgeber time (ZT) with An. gambiae genes in bold blue and Ae. aegypti genes in red. (B) Transcription profiles of genes rhythmic in both species as well as Ae. aegypti transient receptor potential (trp). An. gambiae trp expression was not detected above background levels. Expression values are Z-scored. Day and night are indicated by the horizontal white/black bars below the chart. The shift in the presentation of the beginning and end of expression profiles reflects differences in experimental design between Anopheles and Aedes collections. Mosquito visual gene identities and functions are based on homology to Drosophila and are presumed similar in Anopheles and Aedes mosquitoes [120, 121, 126]. For the full set of An. gambiae vision genes found rhythmic, see Rund et al. 2011 [30]. All data shown are from LD heads.