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Table 1 List of the top five ranking up- and downregulated genes based on the RNA-seq sense strand data

From: Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro

Rank

Direction of expression

Ensembl Gene ID

Gene symbol

Gene name

Log2fold change

AdjustedP-value

1

Upregulated

ENSBTAG00000023064

Not available

Uncharacterized protein

8.41

7.62 × 10-21

2

Upregulated

ENSBTAG00000017981

ADRB3

adrenergic, beta-3-, receptor

8.01

2.48 × 10-17

3

Upregulated

ENSBTAG00000002150

IL17A

interleukin 17A

7.71

1.37 × 10-14

4

Upregulated

ENSBTAG00000022396

SAA3

serum amyloid A 3

7.50

7.67 × 10-114

5

Upregulated

ENSBTAG00000010433

M-SAA3.2

mammary serum amyloid A3.2

6.95

5.26 × 10-41

1

Downregulated

ENSBTAG00000013810

GABBR2

gamma-aminobutyric acid (GABA) B receptor, 2

−6.67

5.49 × 10-08

2

Downregulated

ENSBTAG00000020261

CDH26

cadherin 26

−5.68

4.25 × 10-18

3

Downregulated

ENSBTAG00000004662

SLC16A12

solute carrier family 16, member 12 (monocarboxylic acid transporter 12)

−5.52

3.01 × 10-16

4

Downregulated

ENSBTAG00000017504

FAIM2

Fas apoptotic inhibitory molecule 2

−4.40

6.53 × 10-12

5

Downregulated

ENSBTAG00000017151

SH3TC2

SH3 domain and tetratricopeptide repeats 2

−4.28

4.29 × 10-10

  1. List of the top most upregulated and downregulated genes in M. bovis-infected samples relative to the control samples are shown (ranked by fold change) based on RNA-seq sense strand data.