Reevaluation of the evolutionary events within recA/RAD51 phylogeny

BMC Genomics

Table 1 Qualitative and quantitative analysis of 17 sub-groups within the Reca/RAD51 superfamily

Groups	No. of seq	Viruses	Meta-GOS	Bacteria	Archea	Eukarya	Pairwise % identity (ave in/btw groups)
recA	243		✓	✓		Pr, Fu, Pl,	61.5\| 24.7
RADA	48				✓		56.8\| 30.0
RADB	31				✓		44.0\| 30.0
RADAB	5				✓		74.5\| 30.0
DMC1	55					Pr, In, Nm, Fu, Pl, Ch	59.2\| 29.9
RAD51	70					Pr, In, Nm, Fu, Pl, Ch	68.7\| 29.6
RAD51C	24					Pr, Pl, Ch	51.5\| 30.0
RAD51B	15					Pl, Ch (Pr)	51.4\| 30.0
RAD51D	18					Pl, Ch (Pr, Fu, In)	48.7\| 30.0
XRCC2	15					Pl, Ch (Pr, In)	46.6\| 30.0
XRCC3	21					Pl, Ch (Pr, In)	48.9\| 30.0
recA-SAR1	10		✓				74.6\| 30.0
Phage SAR1	14	✓	✓				66.5\| 30.0
Phage SAR2	17	✓	✓				73.3\|30.0
Phage UvsX	21	✓	✓				66.6\|30.0
Unknown 1	6		✓				67.4\|30.0
Unknown 2	20		✓		✓		57.1\|30.0

Abbreviations are as follows: Protists (Pr), Insects (In), Nematodes (Nm), Fungi (Fu), Plants (Pl), and Chordate (Ch). Parentheses in RAD51B, D and XRCC2, XRCC3 groups denote species which are putative members of the respective group but were not included in the phylogenetic inference because they disrupt the overall topology and cannot be unambiguously assigned. These 14 sequences are listed below along with their GI numbers and species names.
XRCC2_303290256_Micromonas_pusilla_Plants, XRCC2_332024988_Acromyrmex_echinatior_Insecta, XRCC2_255074101_Micromonas_Plants, XRCC2_66803939_Dictyostelium_discoideum_Protists, XRCC2_281210087_Polysphondylium_pallidum_Protists, RAD51D_170071670_Culex_quinquefasciatus_Insecta, RAD51D_321474080_Daphnia_pulex_Animal, RAD51D_111226459_Dictyostelium_discoideum_Protist, XRCC3_307191609_Harpegnathos_saltator_Insecta, XRCC3_281201100_Polysphondylium_pallidum_Protist, XRCC3_170044836_Culex_quinquefasciatus_Insecta, XRCC3_307171500_Camponotus_floridanus_Insecta, RAD51B_45685353_Chlamydomonas_reinhardtii_Protists, ID9_Unknown2_118195642_Cenarchaeum_symbiosum_Protists.

ISSN: 1471-2164