Figure 2
From: Spir2; a novel QTL on chromosome 4 contributes to susceptibility to pneumococcal infection in mice
Infection phenotypes for CCBAF2 mice heterozygous or homozygous for CBA/Ca or homozygous for BALB/c alleles at SNP 4_80. (A) Kaplan-Meier survival curves, showing the cumulative survival (over time after intranasal infection with S. pneumoniae) for CCBAF2 mice heterozygous, homozygous for CBA/Ca or homozygous for BALB/c at SNP 4_80. Statistical significance (compared to heterozygote, pair-wise comparison with the Log Rank test) is indicated by p values on the graph. (B) Average numbers of S. pneumoniae (Log CFU/ml) in the blood at 24 hours post-infection for CCBAF2 mice grouped by their genotype at SNP 4_80. Error bars represent the standard error of the mean. The numbers of mice in each group are shown in brackets. Statistical significance (compared to heterozygote, unpaired t-test) is indicated by p values on the chart.