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Table 1 Comparison of LCE3C_LCE3B-del aCGH values with LCE3C_LCE3B-del and rs4112788 genotypes in 13 world populations

From: Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders

    LCE3C/LCE3B genotype frequency (%) LCE3C/LCE3B allele frequency (%) rs4112788 genotype frequency (%)
Geographic Region Population (ID) aCGH intensity values (respect to YRI*) +/+ +/− −/− + AA AG GG
Sub-Saharan Africans Pygmies* (PYG) −0.13 38.6 52.3 9.1 64.77 35.23 0 13.64 86.36
  Yoruba (YRI) 0* 36.4 59.1 4.5 65.91 34.09 0 28.57 71.43
  Bantu (BAN) −0.03 44.4 55.6 - 72.22 27.78 0 50.00 50.00
North-Africans/Middle East Mozabite*# (ALG) −0.3 11.5 42.3 46.2 32.69 67.31 0 21.43 78.57
  Bedouin* (BED) −0.21 19.4 55.6 25 47.22 52.78 14.63 53.66 31.71
Europians French (FRA) −0.2 22.2 37 40.7 40.74 59.26 16.67 41.67 41.67
Southern Asians Brahui# (BRA) −0.31 22.7 40.9 36.4 43.18 56.82 21.74 43.48 34.78
  Hazara (HAZ) −0.15 58.9 41.1 0 79.41 20.59 43.75 56.25 0
Eastern Asians Han# (CHB) −0.26 14.7 47.1 38.2 38.24 61.76 0 52.17 47.83
  Yakut* (YAK) −0.12 63.6 27.3 9.1 77.27 22.73 50.00 31.82 18.18
Oceania Papuan-Melanesian (OCE) −0.18 31.4 37.1 31.4 50.00 50.00 26.47 41.18 32.35
Americans PIMA# −0.67 9.1 31.9 59.1 25.00 75.00 9.09 36.36 54.55
  MAYA# −0.27 9.5 57.1 33.3 38.10 61.90 7.14 57.14 35.71
  1. Comparison of aCGH log2 ratio values for each population analysed in the array against the Yoruba population with the CNV genotypes and allele frequencies found by PCR, and with the genotype frequency of tag SNP rs4112788.
  2. *Isolated populations.
  3. # Populations with values significantly low for a copy-number loss by our algorithm.