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Table 4 Summary of regression analysis (Group 4 & regression model2)

From: Translational signatures and mRNA levels are highly correlated in human stably expressed genes

Predictor

Coeficient (95% CI)

Significance

Contribution* (95% CI)

tAi

25.0(20.14,29.94)

< 2e-16

0.28(0.13,0.43)

Log(L3utr)

−0.14(-0.23,-0.05)

0.00355

0.17(0.08,0.26)

dG

0.02(0.01,0.03)

0.03023

0.01(0.00,0.02)

Cys

−22.39(-26.59,-18.20)

< 2e-16

0.18(0.10,0.26)

Glu

−5.34(-8.96,-1.72)

0.00396

0.01(0.00-0.02)

Gln

−10.58(-17.53,-3.63)

0.00292

0.06(0.01,0.11)

His

−14.64(-23.84,-5.44)

0.00189

0.21(0.10,0.32)

Leu

−7.92(-11.85,-3.99)

8.75e-05

0.05(0.01,0.09)

Arg

5.60(1.10,10.10)

0.01488

0.01(0.00-0.01)

  1. *Relative importance to log(expression) normalized to sum 100%.
  2. L3utr length of 3 UTR, dG minimum folding energy. tAi tRNA adaptation index.