Gene symbol | Entrez gene name | TBI-I fold change | TBI-C fold change | TBI-I/TBI-C ratio | Molecule type |
---|---|---|---|---|---|
Extracellular space | Â | Â | Â | Â | Â |
CSF1 | colony stimulating factor 1 (macrophage) | 3.70 | 2.09 | 1.77 | cytokine |
SPP1 | secreted phosphoprotein 1 | 37.91 | 2.37 | 15.99 | cytokine |
ERAP1 | endoplasmic reticulum aminopeptidase 1 | 5.84 | 3.05 | 1.92 | peptidase |
LCN2 | lipocalin 2 | 71.82 | 3.90 | 18.44 | transporter |
TGFB2 | transforming growth factor, beta 2 | -4.00 | -7.97 | 1.99 | growth factor |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 58.49 | 2.51 | 23.31 | other |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 5.81 | 2.03 | 2.86 | other |
TIMP1 | TIMP metallopeptidase inhibitor 1 | 38.49 | 2.10 | 18.32 | other |
Plasma membrane | Â | Â | Â | Â | Â |
HLA-C | major histocompatibility complex, class I, C | 9.30 | 3.66 | 2.54 | transmembrane receptor |
IGSF6 | immunoglobulin superfamily, member 6 | 22.46 | 3.27 | 6.87 | transmembrane receptor |
IL13RA1 | interleukin 13 receptor, alpha 1 | 4.53 | 2.27 | 1.99 | transmembrane receptor |
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 2.31 | -3.28 | 7.57 | transmembrane receptor |
THBD | thrombomodulin | 3.85 | 2.09 | 1.84 | transmembrane receptor |
KCNN4 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 3.09 | -9.43 | 29.12 | ion channel |
EGFR | epidermal growth factor receptor | 6.77 | 2.37 | 2.85 | kinase |
MGLL | monoglyceride lipase | -7.85 | -18.15 | 2.31 | enzyme |
CD44 | CD44 molecule (Indian blood group) | 15.56 | 2.40 | 6.49 | other |
CLEC12A | C-type lectin domain family 12, member A | 10.92 | 2.15 | 5.08 | other |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 4.83 | 2.68 | 1.80 | other |
SDC1 | syndecan 1 | 13.68 | 2.57 | 5.33 | other |
Cytoplasm | Â | Â | Â | Â | Â |
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 6.94 | 3.78 | 1.84 | kinase |
PDE4B | phosphodiesterase 4B, cAMP-specific | 5.60 | 2.36 | 2.37 | enzyme |
PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 4.49 | 2.21 | 2.03 | phosphatase |
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 2.39 | -2.11 | 5.04 | transporter |
HSPB1 | heat shock 27 kDa protein 1 | 46.92 | 2.64 | 17.78 | other |
LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 6.08 | 2.80 | 2.17 | other |
LSP1 | lymphocyte-specific protein 1 | 11.72 | 2.14 | 5.47 | other |
MYO1F | myosin IF | 4.27 | 2.26 | 1.89 | other |
Nucleus | Â | Â | Â | Â | Â |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | -3.40 | -6.13 | 1.80 | transcription regulator |
CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 11.27 | 2.04 | 5.53 | transcription regulator |
DEK | DEK oncogene | -3.01 | -7.35 | 2.45 | transcription regulator |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 4.22 | -3.77 | 15.91 | transcription regulator |
MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 28.18 | 7.33 | 3.85 | enzyme |
TOP2A | topoisomerase (DNA) II alpha 170 kDa | 2.26 | -2.41 | 5.44 | enzyme |
THRA | thyroid hormone receptor, alpha | -2.80 | -11.52 | 4.12 | ligand-dependent nuclear receptor |
CCND1 | cyclin D1 | 2.15 | -2.03 | 4.36 | other |
Unknown | Â | Â | Â | Â | Â |
Slpi (includes others) | secretory leukocyte peptidase inhibitor | 82.91 | 3.12 | 26.58 | other |