Origins of amyloid-β

BMC Genomics

Table 2 Synapomorphic frequencies of domains within each branch

Domain	APL-1	APPL-1	AβPP	APLP-2	APLP-1
N-Terminal Signal Peptide	6.41	4.80	11.74	18.47	21.38
E1	13.91	18.36	20.07	13.56	6.54
E2	25.38	13.42	18.49	15.81	24.94
E3	12.50	6.30	1.70	6.63	8.31

APL-1: amyloid precursor like 1 protein; APPL-1: AβPP-like 1 protein; AβPP: amyloid-β precursor protein; APLP-2: amyloid precursor protein like protein 2; APLP-1: amyloid precursor protein like protein 1. This table shows the percentage of synapomorphy accounted for by the N-terminal signal peptide and the three major conserved regions of the peptide sequences within each branch of the phylogenetic trees.

ISSN: 1471-2164