Table 1 Biological features currently supported by the Seurat software, and their respective input files
Feature | Input data sources | Optional data sources |
|---|---|---|
Somatic base substitutions | 1. Normal DNA BAM | Normal RNA BAM |
2. Tumor DNA BAM | Tumor RNA BAM | |
Somatic insertions/deletions | 1. Normal DNA BAM | Normal RNA BAM |
2. Tumor DNA BAM | Tumor RNA BAM | |
Somatic loss of heterozygosity | 1. Normal DNA BAM | Normal RNA BAM |
2. Tumor DNA BAM | Tumor RNA BAM | |
Allelic imbalance | 1. RNA BAM | -- |
2. DNA BAM | Â | |
Somatic structural variance | 1. Normal DNA BAM | -- |
2. Tumor DNA BAM | Â |