Alterations in expression of endometrial genes coding for proteins secreted into the uterine lumen during conceptus elongation in cattle

BMC Genomics

Table 3 A summary of the overall effects of day, pregnancy status and progesterone (P4) concentrations on endometrial expression of selected genes that encode for secreted proteins

Gene name	Gene description	Day	Pregnancy	Day *Pregnancy	P4	Protein detected in ULF
APOA1	Apolipoprotein A-I	*	*	-	*	YES
ARSA	Arylsulfatase A	***	-	-	-	YES
CYR61	Cysteine-rich, angiogenic inducer, 61	-	-	-	-	ND
DCN	Decorin Precursor (Bone proteoglycan II)(PG-S2)	**	*	-	-	ND
LCAT	Lecithin-cholesterol acyltransferase	**	-	*	*	YES
MGP	Bos taurus matrix Gla protein (MGP), mRNA.	-	-	-	*	ND
MUC13	Mucin 13, cell surface associated	**	-	-	-	ND
NCDN	Neurochondrin	**	*	*	-	YES
NMN	Neuromedin N	-	-	*	*	ND
NPNT	Nephronectin	**	*	*	*	ND
NXPH3	Neurexophilin 3	*	-	-	*	ND
PENK	Proenkephalin A Precursor [Contains Synenkephalin;Met-enkephalin(Opioid growth factor)(OGF);Met-enkephalin-Arg-Gly-Leu;Leu-enkephalin;Enkelytin;Met-enkephalin-Arg-Phe]	**	-	-	*	ND
PLIN2	Adipophilin (Adipose differentiation-related protein)(ADRP)	-	*	*	*	YES
TINAGL1	Tubulointerstitial nephritis antigen-like 1	**	*	-	*	ND

Protein encoded for by these genes were detected in uterine luminal fluid during the period of conceptus elongation (Day 13) through to initiation of implantation (Day 19) by either nano LC MS/MS or iTraq analyses. Significance is set at P<0.05 (*), P<0.01 (**) or P<0.001 (***). – denotes no significant effect of a given treatment. ND = protein product not detected by either method.